860692-53-1

Basic information

• Product Name: 4-acetylamino-2-isopropoxy-benzoic acid methyl ester
• Synonyms: 4-acetylamino-2-isopropoxy-benzoic acid methyl ester
• CAS NO: 860692-53-1
• Molecular Weight: 251.282
• Mol File: 860692-53-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-acetylamino-2-isopropoxy-benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-acetylamino-2-isopropoxy-benzoic acid methyl ester(860692-53-1)
• EPA Substance Registry System: 4-acetylamino-2-isopropoxy-benzoic acid methyl ester(860692-53-1)

Safety Data

• Hazardous Substances Data: 860692-53-1(Hazardous Substances Data)

Upstream product

• 75-30-9 2-iodo-propane 
• 4093-28-1 methyl 4-acetamido-2-hydroxybenzoate 
• 75-26-3 isopropyl bromide 

Downstream Products

• 1028126-90-0 C₁₃H₁₆N₂O₆ 
• 4093-28-1 methyl 4-acetamido-2-hydroxybenzoate 
• 172093-27-5 4-amino-5-chloro-2-(iso-propoxy)benzoic acid 
• 2486-78-4 4-amino-2-isopropoxybenzoic acid 
• 172093-28-6 methyl 4-acetylamino-5-chloro-2-isopropoxybenzoate 

Relevant articles and documents

Design, synthesis, inhibitory activity, and SAR studies of hydrophobic p-aminosalicylic acid derivatives as neuraminidase inhibitors

A series of hydrophobic p-aminosalicylic acid derivatives containing a lipophilic side chain at C-2 and an amino or guanidine at C-5 were synthesized and evaluated for their ability to inhibit neuraminidase (NA) of influenza A virus (H3N2). All compounds were synthesized in good yields starting from commercially available p-aminosalicylic acid (PAS) using a suitable synthetic strategy. These compounds showed potent inhibitory activity against influenza A NA. Within this series, six compounds, 11, 12, 13e, 16e, 17c, and 18e, have the good potency (IC50 = 0.032-0.049 μM), which are compared to Oseltamivir (IC50 = 0.021 μM) and could be used as lead compounds in the future.