861601-15-2

Basic information

• Product Name: 1-bromo-3-iodo-5-nitrobenzene
• Synonyms: Benzene,1-broMo-3-iodo-5-nitro-;3-Bromo-5-iodonitrobenzene 95%;3-Bromo-5-iodonitrobenzene95%;1-bromo-3-iodo-5-nitrobenzene;3-Bromo-5-iodonitrobenzene;3-Bromo-5-nitroiodobenzene
• CAS NO: 861601-15-2
• Molecular Formula: C₆H₃BrINO₂
• Molecular Weight: 327.90199
• Mol File: 861601-15-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 1-bromo-3-iodo-5-nitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-bromo-3-iodo-5-nitrobenzene(861601-15-2)
• EPA Substance Registry System: 1-bromo-3-iodo-5-nitrobenzene(861601-15-2)

Safety Data

• Hazardous Substances Data: 861601-15-2(Hazardous Substances Data)

Usage

General Description

1-bromo-3-iodo-5-nitrobenzene is a chemical compound with the molecular formula C6H3BrIN2O2. It is a derivative of benzene with bromine, iodine, and nitro functional groups. 1-bromo-3-iodo-5-nitrobenzene is commonly used in organic synthesis as a reagent and intermediate for the production of various pharmaceuticals, agrochemicals, and dyes. It is a yellowish crystalline solid with a melting point of 100-101°C and is insoluble in water but soluble in organic solvents. 1-bromo-3-iodo-5-nitrobenzene is classified as a hazardous chemical and should be handled with care due to its potential health and environmental risks.

Upstream product

• 33348-35-5 2-Brom-6-iod-4-nitroanilin 
• 180624-08-2 4-bromo-2-nitro-6-iodoaniline 
• 875-51-4 4-Bromo-2-nitroaniline 
• 13296-94-1 2-bromo-4-nitroaniline 
• 88-74-4 2-nitro-aniline 
• 99277-71-1 4-bromo-2-nitrobenzoic acid 

Downstream Products

• 31948-87-5 3-Bromo-5-iodoaniline 
• 1000289-33-7 (3-bromo-5-iodophenyl)thiourea 
• 1000289-32-6 1-benzoyl-3-(3-bromo-5-iodophenyl)thiourea 

Relevant articles and documents

Pd-Catalyzed Decarboxylative Ortho-Halogenation of Aryl Carboxylic Acids with Sodium Halide NaX Using Carboxyl as a Traceless Directing Group

A highly regioselective Pd-catalyzed carboxyl directed decarboxylative ortho-C-H halogenation of cheap o-nitrobenzoic acids with NaX (X = I, Br) under aerobic conditions has been established. The utility of the method has been demonstrated by the gram-scale reaction and derivatization of the product. Experimental results have confirmed Pd and Bi played critical roles in the transformation and indicated the transformation might proceed via 2-halo-6-nitrobenzoic acid derivative intermediate.

ANTIBACTERIAL COMPOSITIONS

Compounds of formula (I) have antibacterial activity: wherein: m is 0 or 1 ; Q is hydrogen or cyclopropyl; AIk is an optionally substituted, divalent C1-C6 alkylene, alkenylene or alkynylene radical which may contain an ether (-O-), thioether (-S-) or amino (-NR)- link, wherein R is hydrogen, -CN or C1-C3 alkyl; X is -C(=O)NR6-, -S(O)NR6-, -C(=O)O- or -S(=O)O- wherein R6 is hydrogen, optionally substituted C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, -Cyc, or -( C1-C3 alkyl)-Cyc wherein Cyc is optionally substituted monocyclic carbocyclic or heterocyclic having 3-7 ring atoms; Z is N or CH, or CF; R2 and R3 are as defined in the description.