861691-37-4

Basic information

• Product Name: 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one
• Synonyms: 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one;2''-O-beta-L-Galactopyranosylorientin;2"-O-beta-L-galactopyranosylorientin;2"-O-β-L-Galorientin;Orientin-2''-O-β-L-galactoside;2'-O-β-L-galactopyranosylorientin;Orientin 2''-galactoside
• CAS NO: 861691-37-4
• Molecular Formula: C27H30O16
• Molecular Weight: 610.52
• Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
• Mol File: 861691-37-4.mol
• Article Data: 2

Chemical Properties

• Melting Point: 218-220℃
• Boiling Point: 988.9±65.0 °C(Predicted)
• Appearance: /
• Density: 1.87
• PKA: 6.19±0.40(Predicted)
• CAS DataBase Reference: 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one(861691-37-4)
• EPA Substance Registry System: 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one(861691-37-4)

Safety Data

• Hazardous Substances Data: 861691-37-4(Hazardous Substances Data)

Usage

General Description

2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one is a chemical compound that belongs to the flavonoid class of compounds. It is a natural product found in various fruits and vegetables and is known for its antioxidant properties. 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one has an intricate structure, consisting of multiple phenolic hydroxyl groups and sugar moieties, which contribute to its biological activities. It has been studied for its potential health benefits, including its anti-inflammatory, anti-cancer, and anti-diabetic properties. Additionally, it has been researched for its potential use in the development of pharmaceuticals and nutritional supplements.

Upstream product

• 2956-16-3 uridine 5'-diphospho-D-galactose 
• 7480-94-6 Luteolin-8-C-glucoside 
• 133-89-1 UDP-glucose 

Relevant articles and documents

Characterization of a Highly Selective 2″- O-Galactosyltransferase from Trollius chinensis and Structure-Guided Engineering for Improving UDP-Glucose Selectivity

A novel 2″-O-galactosyltransferase TcOGT4 was discovered from Trollius chinensis. TcOGT4 could regio-specifically catalyze 2″-O-galactosylation of 17 flavone 8-C-β-d-glucosides and shows high preference for UDP-Gal. Molecular docking indicated that Pro361 may play a key role in sugar donor selectivity, and the P361W mutant exhibited significantly enhanced selectivity toward UDP-Glc. A total of 21 products including 17 new compounds were obtained, and 5 of them showed potent COX-2 inhibitory activities. TcOGT4 is the first reported 2″-O-galactosyltransferase for flavone C-glycosides, and could be a powerful biocatalyst to synthesize bioactive flavone glycosides.