86170-43-6

Basic information

• Product Name: N-CBZ-VAL-GLY-ARG P-NITROANILIDE ACETATE SALT
• Synonyms: N-CBZ-VAL-GLY-ARG P-NITROANILIDE ACETATE SALT;N-cbz-val-gly-arg P-nitroanilide*acetate;N-[(benzyloxy)carbonyl]-L-valylglycyl-N-(p-nitrophenyl)-L-argininamide monoacetate;z-val-gly-arg p-nitroanilide acetate salt;N-carbobenzyloxy-Val-Gly-Arg-p-nitroanilide acetate;Einecs 289-197-4;L-ArgininaMide, N-[(phenylMethoxy)carbonyl]-L-valylglycyl-N-(4-nitrophenyl)-, Monoacetate;Z-Val-Gly-Arg-pNA.Hac
• CAS NO: 86170-43-6
• Molecular Formula: C29H40N8O9
• Molecular Weight: 644.68
• EINECS: 289-197-4
• Product Categories: Activity;Chromogenic;Enzyme Substrates
• Mol File: 86170-43-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 1000.1°C at 760 mmHg
• Flash Point: 558.7°C
• Appearance: /
• Vapor Pressure: 0mmHg at 25°C
• Storage Temp.: −20°C
• CAS DataBase Reference: N-CBZ-VAL-GLY-ARG P-NITROANILIDE ACETATE SALT(CAS DataBase Reference)
• NIST Chemistry Reference: N-CBZ-VAL-GLY-ARG P-NITROANILIDE ACETATE SALT(86170-43-6)
• EPA Substance Registry System: N-CBZ-VAL-GLY-ARG P-NITROANILIDE ACETATE SALT(86170-43-6)

Safety Data

• Hazardous Substances Data: 86170-43-6(Hazardous Substances Data)

Usage

General Description

N-CBZ-VAL-GLY-ARG P-NITROANILIDE ACETATE SALT is a chemical compound used in biochemical research and pharmaceutical development. It consists of the amino acid sequence VAL-GLY-ARG, also known as VGR, conjugated to a p-nitroanilide moiety and acetylated with a carbobenzyloxy (CBZ) group. N-CBZ-VAL-GLY-ARG P-NITROANILIDE ACETATE SALT is commonly employed as a substrate in enzymatic assays to study the activity of peptidases such as chymotrypsin and trypsin. The p-nitroanilide group acts as a chromogenic reporter, allowing for the quantification of enzymatic activity, while the acetyl and CBZ groups provide stability and protection to the peptide moiety. N-CBZ-VAL-GLY-ARG P-NITROANILIDE ACETATE SALT is a versatile tool in biochemical research and drug discovery, allowing for the study of peptidase activity and the screening of potential enzyme inhibitors.

InChI:InChI=1/C27H36N8O7.C2H4O2/c1-17(2)23(34-27(39)42-16-18-7-4-3-5-8-18)25(38)31-15-22(36)33-21(9-6-14-30-26(28)29)24(37)32-19-10-12-20(13-11-19)35(40)41;1-2(3)4/h3-5,7-8,10-13,17,21,23H,6,9,14-16H2,1-2H3,(H,31,38)(H,32,37)(H,33,36)(H,34,39)(H4,28,29,30);1H3,(H,3,4)/t21-,23-;/m0./s1