861787-48-6

Basic information

• Product Name: 3,5-dibromo-2-nitro-benzaldehyde
• Synonyms: 3,5-dibromo-2-nitro-benzaldehyde
• CAS NO: 861787-48-6
• Molecular Weight: 308.914
• Mol File: 861787-48-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3,5-dibromo-2-nitro-benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-dibromo-2-nitro-benzaldehyde(861787-48-6)
• EPA Substance Registry System: 3,5-dibromo-2-nitro-benzaldehyde(861787-48-6)

Safety Data

• Hazardous Substances Data: 861787-48-6(Hazardous Substances Data)

Upstream product

• 552-89-6 2-nitro-benzaldehyde 
• 56990-02-4 3,5-dibromobenzaldehyde 

Downstream Products

• 23828-92-4 ambroxol hydrochloride 
• 18683-91-5 ambroxol 
• 860789-75-9 6,8-dibromo-2-phenylquinoline 
• 60912-52-9 3,5-dibromo-2-nitro-benzoic acid 
• 2475-31-2 5,7-dibromo-2-(5,7-dibromo-1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,2-dihydro-3H-indol-3-one 
• 50910-55-9 3,5-dibromo-2-amino benzaldehyde 

Relevant articles and documents

Ambroxol hydrochloride synthetic method

The invention belongs to the field of pharmaceutical synthesis and particularly discloses a synthesis method of ambroxol hydrochloride. The synthesis method comprises the steps of brominating o-nitrobenzaldehyde serving as a starting raw material to obtain 2-nitro-3, 5-dibromobenzaldehyde; reacting the obtained 2-nitro-3, 5-dibromobenzaldehyde and trans-4-aminocyclohexanol; and then, reducing and salifying hydrochloride to finally prepare ambroxol hydrochloride. The synthesis method disclosed by the invention is low in raw material cost, simple in operation, safe and environment-friendly, capable of simplifying the production process and increasing the yield and purity of products and suitable for industrial production.