86181-08-0

Basic information

• Product Name: cis-(±)-1-phenyl-2-(aminomethyl)-N,N-diethylcyclopropanecarboxamide hydrochloride
• Synonyms: cis-(±)-1-phenyl-2-(aminomethyl)-N,N-diethylcyclopropanecarboxamide hydrochloride
• CAS NO: 86181-08-0
• Molecular Weight: 282.813
• Mol File: 86181-08-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: cis-(±)-1-phenyl-2-(aminomethyl)-N,N-diethylcyclopropanecarboxamide hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: cis-(±)-1-phenyl-2-(aminomethyl)-N,N-diethylcyclopropanecarboxamide hydrochloride(86181-08-0)
• EPA Substance Registry System: cis-(±)-1-phenyl-2-(aminomethyl)-N,N-diethylcyclopropanecarboxamide hydrochloride(86181-08-0)

Safety Data

• Hazardous Substances Data: 86181-08-0(Hazardous Substances Data)

Upstream product

• 63106-93-4 1-phenyl-3-oxa-bicyclo[3.1.0]hexan-2-one 
• 105310-09-6 milnacipran 
• 105310-75-6 (1SR,2RS)-2-((1,3-dioxoisoindolin-2-yl)methyl)-N,N-diethyl-1-phenylcyclopropane carboxamide 
• 1353644-50-4 (1SR,2RS)-2-(chloromethyl)-N,N-diethyl-1-phenylcyclopropane carboxamide 
• 140-29-4 phenylacetonitrile 

Downstream Products

• 1374648-80-2 (1S,2R)-cis-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide (D)-(-)-mandelate 
• 1374648-84-6 (1R,2S)-cis-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide (L)-(+)-mandelate 
• 101152-94-7 (1S,2R)-milnacipran hydrochloride 
• 96847-54-0 (1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropane-1-carboxamide 
• 96847-54-0 (1R,2S)-milnacipran 
• 101152-94-7 (1R,2S)-cis-milnacipran hydrochloride 
• 105310-09-6 milnacipran 
• 105310-28-9 (+/-)-(Z)-1-phenyl-2-(aminomethyl)cyclopropanecarboxylic acid hydrochloride 

Relevant articles and documents

Drug intermediate as well as preparation and application thereof

The invention designs a drug intermediate III, and the structural formula of the drug intermediate III is shown in the specification.

An Efficient Synthesis of Milnacipran Hydrochloride via Reductive Amination of Aldehyde

An efficient synthesis of milnacipran hydrochloride has been accomplished. The important application of this paper is the reductive amination of aldehyde to primary amine with water soluble reagents. This method provides a high yield of primary amine as t

PROCESS FOR THE PREPARATION OF (±M1R(S), 2SRR)L-2-(AMINOMETHYL)-N,N-DIETHYL-L-PHENYLCYCLOPROPANE CARBOXAMIDE HYDROCHLORIDE

The present invention relates to an improved process for the preparation of (±)-[1R(S),2S(R)]-2-(aminomethyl)-N,N-diethyl-l-phenylcyclopropane carboxamide hydrochloride compound of formula- la.