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861840-51-9

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861840-51-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 861840-51-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,1,8,4 and 0 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 861840-51:
(8*8)+(7*6)+(6*1)+(5*8)+(4*4)+(3*0)+(2*5)+(1*1)=179
179 % 10 = 9
So 861840-51-9 is a valid CAS Registry Number.

861840-51-9Downstream Products

861840-51-9Relevant articles and documents

EGFR PROTEOLYSIS TARGETING CHIMERIC MOLECULES AND ASSOCIATED METHODS OF USE

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Paragraph 0076; 00761, (2018/07/29)

The present disclosure relates to bifunctional compounds, which find utility as modulators of receptor tyrosine kinase (RTK) proteins. In particular, the present disclosure is directed to bifunctional compounds, which contain on one end a ligand which binds to an E3 ubiquitin ligase and on the other end a moiety which binds a target protein, such that the target protein is placed in proximity to the ubiquitin ligase to effectuate ubiquitination, and therefore, degradation (and inhibition) of the target protein. The present disclosure exhibits a broad range of pharmacological activities associated with degradation/inhibition of target protein. Diseases or disorders that result from aggregation or accumulation of the target protein are treated or prevented with compounds and compositions of the present disclosure.

Synthesis of 2-substituted β-cyclodextrin derivatives with a hydrolytic activity against the organophosphorylester paraoxon

Masurier, Nicolas,Estour, Franeois,Froment, Marie-Therese,Lefevre, Bertrand,Debouzy, Jean-Claude,Brasme, Bernard,Masson, Patrick,Lafont, Olivier

, p. 615 - 623 (2007/10/03)

β-Cyclodextrin was substituted by an iodosobenzoic acid derivative to create a catalytic hydrolytic activity against neurotoxic organophosphorus agents. The catalytic moiety was introduced on a secondary hydroxy group at the position 2 of a glucose unit.

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