861852-12-2Relevant articles and documents
Synthesis of dioxane-based antiviral agents and evaluation of their biological activities as inhibitors of Sindbis virus replication
Kim, Ha Young,Kuhn, Richard J.,Patkar, Chinmay,Warrier, Ranjit,Cushman, Mark
, p. 2667 - 2679 (2007)
The crystal structure of the Sindbis virus capsid protein contains one or two solvent-derived dioxane molecules in the hydrophobic binding pocket. A bis-dioxane antiviral agent was designed by linking the two dioxane molecules with a three-carbon chain ha