861853-88-5

Basic information

• Product Name: Methanone, [(4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-diyl]bis[(4-methoxyphenyl)-
• CAS NO: 861853-88-5
• Molecular Formula: C21H22O6
• Molecular Weight: 370.402
• Mol File: 861853-88-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Methanone, [(4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-diyl]bis[(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, [(4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-diyl]bis[(4-methoxyphenyl)-(861853-88-5)
• EPA Substance Registry System: Methanone, [(4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-diyl]bis[(4-methoxyphenyl)-(861853-88-5)

Safety Data

• Hazardous Substances Data: 861853-88-5(Hazardous Substances Data)

Upstream product

• 63126-29-4 (4R,5R)-2,2,N,N,N',N'-hexamethyl-1,3-dioxolane-4,5-dicarboxamide 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 177283-77-1 (4R,5R)-N,N'-dimethoxy-N,N',2,2-tetramethyl-1,3-dioxolane-4,5-dicarboxamide 

Downstream Products

• 861854-00-4 (1R,2R,3R,4R)-1,4-Dimethoxy-1,4-bis-(4-methoxy-phenyl)-butane-2,3-diol 
• 929217-60-7 (-)-{(4R,5R)-2,2-dimethyl-5-[(R)-2,2,2-trifluoro-1-hydroxy-1-(4-methoxyphenyl)ethyl]-[1,3]dioxolan-4-yl}-(4-methoxyphenyl)methanone 
• 861853-97-6 (4S,5S)-4,5-Bis-[(R)-methoxy-(4-methoxy-phenyl)-methyl]-2,2-dimethyl-[1,3]dioxolane 

Relevant articles and documents

Enantiopure quaternary α-trifluoromethyl-α-alkoxyaldehydes from L-tartaric acid derived ketoamides

(Chemical Equation Presented) The diastereoselective nucleophilic trifluoromethylation of a range of ketoamides derived from L-tartaric acid has been studied. TMSCF3 in the presence of a catalytic amount of K 2CO3 in DMF has been identified as the conditions leading to the highest diastereoselectivities. A sequential one-pot reaction trifluoromethylation-etherification of the trifluoromethylcarbinol has been developed. Only one further one-pot reaction, ketal hydrolysis-oxidative cleavage, led to the final α-trifluoromethylated α-alkoxy-aldehydes. This procedure was applied to the preparation of a series of enantiopure aryl, heteroaryl, and alkyl α-trifluoromethyl-α-alkoxyaldehydes.

Nucleophilic addition reactions of 1,4-diketones derived from tartaric acid: Synthesis of TADDOL analogues

A systematic investigation of the reduction and Grignard reagents addition to 1,4-diketones derived from tartaric acid was carried out. It was found that the reduction proceeded with high selectivity using K-Selectride as the reducing agent; while Grignar