861928-20-3 Usage
Description
5-Bromo-4-fluoro-2-iodotoluene is a chemical compound with the molecular formula C7H5BrFI. It is a derivative of toluene and contains bromine, fluorine, and iodine substituents. 5-Bromo-4-fluoro-2-iodotoluene's structure consists of a benzene ring with a bromine atom in the meta position, a fluorine atom in the para position, and an iodine atom in the ortho position relative to the methyl group.
Uses
Used in Pharmaceutical Industry:
5-Bromo-4-fluoro-2-iodotoluene is used as a building block in organic synthesis for the production of various pharmaceutical compounds. Its unique structure with multiple substituents allows for the creation of diverse molecules with potential therapeutic applications.
Used in Agrochemical Industry:
5-Bromo-4-fluoro-2-iodotoluene is also used in the agrochemical industry for the synthesis of various compounds. Its versatile structure enables the development of new agrochemicals with improved properties, such as enhanced efficacy and selectivity.
It is important to handle 5-Bromo-4-fluoro-2-iodotoluene with proper safety precautions due to its potential hazards.
Check Digit Verification of cas no
The CAS Registry Mumber 861928-20-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,1,9,2 and 8 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 861928-20:
(8*8)+(7*6)+(6*1)+(5*9)+(4*2)+(3*8)+(2*2)+(1*0)=193
193 % 10 = 3
So 861928-20-3 is a valid CAS Registry Number.
861928-20-3Relevant articles and documents
Halogen-lithium exchange between substituted dihalobenzenes and butyllithium: Application to the regioselective synthesis of functionalized bromobenzaldehydes
Da?browski, Marek,Kubicka, Joanna,Luliński, Sergiusz,Serwatowski, Janusz
, p. 6590 - 6595 (2007/10/03)
Halogen-lithium interconversion reactions between unsymmetrically substituted mono- and bifunctional dihalobenzenes C6H 3XHal2 and C6H2XYHal2 (Hal=Br, I; X, Y=F, OR, CF3, CH(OMe)2) and butyllithium were investigated. The resultant organolithium intermediates were converted into the corresponding benzaldehydes in moderate to good yields. As a rule, bromine atoms in the position ortho to the functional group were replaced preferentially with lithium. Intramolecular competition experiments with bifunctional systems revealed that fluorine is capable of activating the neighboring bromine atom more strongly than methoxy and dimethoxymethyl groups. On the replacement of the non-activated bromine with iodine a complete reversal of this reactivity pattern can be accomplished due to the preferred iodine-lithium exchange.
