86207-61-6

Basic information

• Product Name: 1-Piperidinecarboxylic acid, 4-hydroxy-, (4-nitrophenyl)methyl ester
• CAS NO: 86207-61-6
• Molecular Formula: C13H16N2O5
• Molecular Weight: 280.28
• Mol File: 86207-61-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-Piperidinecarboxylic acid, 4-hydroxy-, (4-nitrophenyl)methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperidinecarboxylic acid, 4-hydroxy-, (4-nitrophenyl)methyl ester(86207-61-6)
• EPA Substance Registry System: 1-Piperidinecarboxylic acid, 4-hydroxy-, (4-nitrophenyl)methyl ester(86207-61-6)

Safety Data

• Hazardous Substances Data: 86207-61-6(Hazardous Substances Data)

Upstream product

• 5382-17-2 piperidin-4-ol hydrochloride 
• 4457-32-3 4-nitrobenzyl chloroformate 
• 86224-71-7 4-nitrobenzyl 4-oxopiperidine-1-carboxylate 

Downstream Products

• 352305-59-0 7-[1-(4-Nitrobenzyloxycarbonyl)piperidin-4-yl]-thioimidazo[5,1-b]thiazole 

Relevant articles and documents

1-METHYLCARBAPENEM DERIVATIVES

The present invention relates to 1-methylcarbapenem compounds having excellent antibacterial activity, pharmacologically acceptable ester derivatives thereof, pharmacologically acceptable salts thereof, pharmaceutical compositions (particularly antibacterial agents) containing them as active ingredient, use of the compounds, ester derivatives or salts thereof for preparing such pharmaceutical compositions and a method of preventing or treating diseases (particularly bacterial infections) in which a pharmacologically effective amount of the compound, ester derivative or salt is administered to a warm-blooded animal (particularly a human being). The 1-methylcarbapenem compounds of the present invention are represented by the general formula (I): wherein:R1 is a group represented by the formula COOR3 (wherein R3 represents a hydrogen atom, a C1-C6 alkyl group or the like), a group represented by the formula CONR4R5 (wherein R4 and R5 each independently represent a hydrogen atom, a C1-C6 alkyl group which may be substituted or the like), a cyano group, a group represented by the formula CH2OR6 (wherein R6 represents a hydrogen atom, a C1-C6 alkyl group or the like) or a group represented by the formula CH2NR7R8 (wherein R7 represents a hydrogen atom, a C1-C6 alkyl group or the like, and R8 represents a hydrogen atom, a C1-C6 alkyl group, a C1-C6 alkanoyl group, a C1- C6 alkoxycarbonyl group or the like);R2 represents a hydrogen atom or a C1-C6 alkyl group;n represents 1, 2 or 3; andX represents a sulfur atom or an oxygen atom.