862088-18-4

Basic information

• Product Name: Benzonitrile, 3-chloro-5-fluoro-2-hydroxy-
• Synonyms: Benzonitrile, 3-chloro-5-fluoro-2-hydroxy-
• CAS NO: 862088-18-4
• Molecular Formula: C₇H₃ClFNO
• Molecular Weight: 171.56
• Mol File: 862088-18-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzonitrile, 3-chloro-5-fluoro-2-hydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 3-chloro-5-fluoro-2-hydroxy-(862088-18-4)
• EPA Substance Registry System: Benzonitrile, 3-chloro-5-fluoro-2-hydroxy-(862088-18-4)

Safety Data

• Hazardous Substances Data: 862088-18-4(Hazardous Substances Data)

Downstream Products

• 862089-29-0 3-chloro-2-cyanomethoxy-5-fluorobenzonitrile 

Relevant articles and documents

NOVEL BENZOFURAN DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USES OF THESE

[From equivalent EP1710233A1] The present invention provides compounds represented by general formula (I): or pharmaceutical acceptable salts thereof, wherein R1 is hydrogen or lower alkyl; R2 is lower alkyl, halo-lower alkyl, cycloalkyl, heterocycloalkyl, aryl, aralkyl, arylalkenyl, aryloxy-lower alkyl, heteroaryl, heteroaryl-lower alkyl, etc; R3, R4, R5 and R6 are each hydrogen, halogen, cyano, lower alkyl, halo-lower alkyl, lower alkoxy, hydroxy, aryl, etc; provided that at least one of R3, R4, R5 and R6 is other than hydrogen. Compound (I) of the present invention shows a potent adenosine A2A receptor antagonistic activity, and are useful for treating or preventing a disease mediated by adenosine A2A receptors such as motor function disorders, depression, anxiety disorders, cognitive function disorders, cerebral ischemia disorders, restless legs syndrome and the like.