862120-91-0

Basic information

• Product Name: C₁₈H₂₃NO₄
• Synonyms: C₁₈H₂₃NO₄
• CAS NO: 862120-91-0
• Molecular Weight: 317.385
• Mol File: 862120-91-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₁₈H₂₃NO₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₂₃NO₄(862120-91-0)
• EPA Substance Registry System: C₁₈H₂₃NO₄(862120-91-0)

Safety Data

• Hazardous Substances Data: 862120-91-0(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 151907-80-1 (1R,4S)-4-[(tert-butoxycarbonyl)amino]cyclopent-2-ene-1-carboxylic acid 
• 134003-04-6 (1R,4S)-4-aminocyclopenten-2-ene-1-carboxylic acid 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 625098-83-1 (1S,4R)-1-amino-4-benzyloxycarbonyl-cyclopent-2-ene hydrochloride 
• 862120-92-1 C₂₁H₂₉NO₄ 
• 625098-84-2 C₁₈H₂₃NO₃ 
• 625098-85-3 C₂₃H₂₈F₃NO₄ 

Relevant articles and documents

AMINOCYCLOPENTYL PYRIDOPYRAZINONE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY

Compounds of Formula I and Formula II (wherein A, E, j, k, m, n, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R15, R16, R17, R18, R19, R24, R25, R26, R27, R28, R29, R30, R31, R32, R33, R34, X, Y and Z are as defined herein) which are modulators of chemokine receptor activity and are useful in the prevention or treatment of certain inflammatory and immunoregulatory disorders and diseases, allergic diseases, atopic conditions including allergic rhinitis, dermatitis, conjunctivitis, and asthma, as well as autoimmune pathologies such as rheumatoid arthritis and atherosclerosis. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which chemokine receptors are involved.

TETRAHYDROPYRANYL CYCLOPENTYL TETRAHYDROISOQUINOLINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY

The present invention is directed to compounds of the formula I: I(wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n and the dashed line are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.