862130-14-1

Basic information

• Product Name: 2,2'-ethylidenebis(4,6-di-tert-butylphenyl)-4-nitrophenylphosphite
• Synonyms: 2,2'-ethylidenebis(4,6-di-tert-butylphenyl)-4-nitrophenylphosphite
• CAS NO: 862130-14-1
• Molecular Weight: 589.755
• Mol File: 862130-14-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,2'-ethylidenebis(4,6-di-tert-butylphenyl)-4-nitrophenylphosphite(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2'-ethylidenebis(4,6-di-tert-butylphenyl)-4-nitrophenylphosphite(862130-14-1)
• EPA Substance Registry System: 2,2'-ethylidenebis(4,6-di-tert-butylphenyl)-4-nitrophenylphosphite(862130-14-1)

Safety Data

• Hazardous Substances Data: 862130-14-1(Hazardous Substances Data)

Upstream product

• 100-02-7 4-nitro-phenol 
• 35958-30-6 2,2-ethylidenebis(4,6-tert-butylphenol) 

Relevant articles and documents

Method of synthesizing compounds having a phosphorus-fluorine-18 bond

Provided are methods for synthesizing radiotracers, including no carrier added (n.c.a.) tracers suitable as PET scan tracers that contain a 18F—P bond. The radiolabeled products may be synthesized from precursors including phosphorus(V) and/or phosphorus (III) atoms bound to a suitable leaving group or group(s). For example, precursors incorporating a nitrophenoxy leaving group bound to a phosphorus(V) atom tend to exhibit an acceptable combination of stability and reactivity and also tend to allow the precursor compound(s) to be separated more easily from the 18F-labeled products. The methods disclosed herein for producing radiolabeled compounds incorporating a P—18F chemistry may particularly useful radiolabeling oligonucleotides, phospholipids, phosphorilated proteins, sugars and steroids for use as PET radiotracer compounds for medical imaging applications.