862133-68-4

Basic information

• Product Name: 2-[6-(2,4,6-triisopropyl-phenylselanyl)-hex-5-ynyloxy]-tetrahydro-pyrane
• Synonyms: 2-[6-(2,4,6-triisopropyl-phenylselanyl)-hex-5-ynyloxy]-tetrahydro-pyrane
• CAS NO: 862133-68-4
• Molecular Weight: 463.562
• Mol File: 862133-68-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-[6-(2,4,6-triisopropyl-phenylselanyl)-hex-5-ynyloxy]-tetrahydro-pyrane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[6-(2,4,6-triisopropyl-phenylselanyl)-hex-5-ynyloxy]-tetrahydro-pyrane(862133-68-4)
• EPA Substance Registry System: 2-[6-(2,4,6-triisopropyl-phenylselanyl)-hex-5-ynyloxy]-tetrahydro-pyrane(862133-68-4)

Safety Data

• Hazardous Substances Data: 862133-68-4(Hazardous Substances Data)

Upstream product

• 71518-96-2 bis(2,4,6-triisopropylphenyl)diselenide 
• 21524-34-5 2,4,6-triisopropyl-1-bromobenzene 
• 1720-37-2 2-(hex-5-yn-1-yloxy)tetrahydro-2H-pyran 
• 130248-05-4 2,4,6-triisopropylbenzene selenenyl bromide 

Relevant articles and documents

1-Iodo-1-selenoalkenes as versatile alkene 1,1-dianion equivalents. Novel connective approach towards the tetrahydropyran subunit of polycavernoside A

syn-Hydroalumination of 2,4,6-triisopropylphenylselanyl-1-alkynes with DIBAL-H followed by Al/I exchange with I2 afforded exclusively (E)-1-iodo-1-selenoalkenes in good yields. 1-Iodo-1-selenopropene 10 proved to be a convenient 1,1 dianion equivalent, leading to the stereodivergent synthesis of allylsilanes (Z)-6 and (E)-6. Adduct 3, an intermediate in the synthesis of the tetrahydropyran subunit of polycavernoside A, was efficiently synthesised from allylsilane (Z)-6 and aldehyde 7 via an intramolecular Sakurai cyclisation.