862201-26-1Relevant articles and documents
Silver-coordinated aza-pyrrolidone complex, and preparation method and application thereof
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, (2021/07/08)
The invention discloses a silver-coordinated aza-pyrrolidone complex, and a preparation method and application thereof. The complex is composed of an aza-pyrrolidone ligand, a silver metal center and a triphenylphosphine auxiliary ligand, the raw materials are relatively cheap, and the synthesis method is simple; and the prepared complex shows relatively strong absorption in an ultraviolet region and a near-infrared region, and can be excited by near-infrared light, so that the damage of an excitation light source to a biological sample can be weakened, and the complex has relatively deep tissue penetration depth in the field of living body application, and is more suitable for biological imaging and deep photodynamic photo-thermal combined treatment.
Synthesis of Aza-BODIPY boron difluoride PDT agents to promote apoptosis in HeLa cells
Priefer, Ronny,Griffithsa, Justin R.,Ludwiga, Janelle N.,Skelhorne-Grossb, Graham,Greene, Robert S.
, p. 368 - 373 (2012/05/07)
BF2 Chelated azadipyrromethene dyes fluoresce in the near infrared and have potential applications in photodynamic therapy. When irradiated above 600nm these aza-BODIPY compounds react with triplet O 2 in the body to form a reactive
A modular synthesis of unsymmetrical tetraarylazadipyrromethenes
Hall, Michael J.,McDonnell, Shane O.,Killoran, John,O'Shea, Donal F.
, p. 5571 - 5578 (2007/10/03)
A stepwise route to unsymmetrical tetraarylazadipyrromethenes by a condensation of 2,4-diaryl-5-nitroso-pyrroles with 2,4-diarylpyrroles is described. This modular building-block approach allows for the introduction of up to four different aryl substituents on the azadipyrromethene and is tolerant of a varied substituent set. An efficient synthesis of the 2,4-diarylpyrroles building blocks from 1,3-diaryl-4-nitro-butan-1-ones by nitro hydrolysis to a keto-aldehyde and subsequent ammonia condensation reaction has been achieved. The facile conversion of 2,4-diarylpyrroles into their α-nitroso analogues by their reaction with sodium nitrite generated the second building block required for the synthesis.