862259-10-7

Basic information

• Product Name: (Z)-(R)-10-(Benzyl-dimethyl-silanyl)-12-hydroxy-13-methyl-tetradec-10-enoic acid methyl ester
• Synonyms: (Z)-(R)-10-(Benzyl-dimethyl-silanyl)-12-hydroxy-13-methyl-tetradec-10-enoic acid methyl ester
• CAS NO: 862259-10-7
• Molecular Weight: 418.692
• Mol File: 862259-10-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-(R)-10-(Benzyl-dimethyl-silanyl)-12-hydroxy-13-methyl-tetradec-10-enoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-(R)-10-(Benzyl-dimethyl-silanyl)-12-hydroxy-13-methyl-tetradec-10-enoic acid methyl ester(862259-10-7)
• EPA Substance Registry System: (Z)-(R)-10-(Benzyl-dimethyl-silanyl)-12-hydroxy-13-methyl-tetradec-10-enoic acid methyl ester(862259-10-7)

Safety Data

• Hazardous Substances Data: 862259-10-7(Hazardous Substances Data)

Upstream product

• 2777-66-4 methyl 10-undecynoate 
• 862259-09-4 (R)-methyl 12-hydroxy-13-methyl-10-tetradecynoate 
• 1631-70-5 benzyldimethylsilane 

Relevant articles and documents

An alkyne hydrosilylation-oxidation strategy for the selective installation of oxygen functionality

Alkynes bearing propargylic, homopropargylic, and bishomopropargylic hydroxyl groups are shown to serve as precursors for ketone or α-hydroxy ketone functionality. The approach hinges on the intermediacy of vinylsilanes created through regioselective hydrosilylation catalyzed by the complex [Cp*Ru(MeCN)3]-PF6. Several oxidative pathways of linear and cyclic vinylsilanes are studied, and the possibility of diastereoselective epoxidation of cyclic vinylsilanes is demonstrated. The sequences constitute the equivalent of stereoselective aldol, homo-aldol, and bishomo-aldol type processes. The method is applied to a short synthesis of the piperidine alkaloid, spectaline.