862306-55-6Relevant articles and documents
Enantioselective and diastereoselective synthesis of fluorinated dipeptides by late electrophilic fluorination
Mohar, Barbara,Sterk, Damjan,Ferron, Laurent,Cahard, Dominique
, p. 5029 - 5031 (2007/10/03)
A series of optically enriched monofluorinated dipeptides incorporating an α-fluoro-α-amino acid were prepared by enantio- and diastereoselective electrophilic fluorination. This previously unsuccessful approach to fluorinated dipeptides can now be achieved with up to 73:27 enantiomeric ratio and high >98:2 diastereomeric ratio.