862473-26-5

Basic information

• Product Name: (2S,2'S,3''S,4''S)-1-[6'-benzyloxycarbonylamino-2'-(3''-tert-butoxycarbonylamino-2''-oxo-4''-vinyl-piperidin-1''-yl)-hexanoyl]-pyrrolidine-2-carboxylic acid tert-butyl ester
• Synonyms: (2S,2'S,3''S,4''S)-1-[6'-benzyloxycarbonylamino-2'-(3''-tert-butoxycarbonylamino-2''-oxo-4''-vinyl-piperidin-1''-yl)-hexanoyl]-pyrrolidine-2-carboxylic acid tert-butyl ester
• CAS NO: 862473-26-5
• Molecular Weight: 656.82
• Mol File: 862473-26-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,2'S,3''S,4''S)-1-[6'-benzyloxycarbonylamino-2'-(3''-tert-butoxycarbonylamino-2''-oxo-4''-vinyl-piperidin-1''-yl)-hexanoyl]-pyrrolidine-2-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,2'S,3''S,4''S)-1-[6'-benzyloxycarbonylamino-2'-(3''-tert-butoxycarbonylamino-2''-oxo-4''-vinyl-piperidin-1''-yl)-hexanoyl]-pyrrolidine-2-carboxylic acid tert-butyl ester(862473-26-5)
• EPA Substance Registry System: (2S,2'S,3''S,4''S)-1-[6'-benzyloxycarbonylamino-2'-(3''-tert-butoxycarbonylamino-2''-oxo-4''-vinyl-piperidin-1''-yl)-hexanoyl]-pyrrolidine-2-carboxylic acid tert-butyl ester(862473-26-5)

Safety Data

• Hazardous Substances Data: 862473-26-5(Hazardous Substances Data)

Upstream product

• 862473-25-4 (2S,2'S,3''S,2'''S)-1-{6'-benzyloxycarbonylamino-2'-[[3'''-(tert-butoxycarbonylamino-carboxy-methyl)-pent-4'''-enyl]-(9H-fluoren-9-ylmethoxycarbonyl)-amino]-hexanoyl}-pyrrolidine-2-carboxylic acid tert-butyl ester 
• 515173-85-0 (1'S,4S)-4-(1'-ethoxycarbonylmethyl-allyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 515173-88-3 (1'S,4S)-4-[1'-(2''-hydroxy-ethyl)-allyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 2812-46-6 proline tert-butyl ester 
• 134525-18-1 (2E',4S)-4-(2'-ethoxycarbonyl-vinyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 862473-40-3 Fmoc-L-Lys(Cbz)-Pro-OBu^t 
• 86060-82-4 Fmoc-Lys(Z)-OH 
• 88555-03-7 (2S,2'S)-1-(2'-amino-6'-benzyloxycarbonylamino-hexanoyl)-pyrrolidine-2-carboxylic acid tert-butyl ester 
• 862473-24-3 (4S,1'S,1'''S,2''''S)-4-(1'-{2''-[[5'''-benzyloxycarbonylamino-1'''-(2''''-tert-butoxycarbonyl-pyrrolidine-1''''-carbonyl)-pentyl]-(9H-fluoren-9-ylmethoxycarbonyl)-amino]-ethyl}-allyl)-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester 
• 862473-23-2 (4S,1'S,1'''S,2''''S)-4-(1'-{2''-[5'''-benzyloxycarbonylamino-1'''-(2''''-tert-butoxycarbonyl-pyrrolidine-1''''-carbonyl)-pentylamino]-ethyl}-allyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 862473-08-3 (4S,1'S)-2,2-dimethyl-4-[1'-(2''-oxoethyl)allyl]oxazolidine-3-carboxylic acid tert-butyl ester 

Downstream Products

• 862473-34-5 (2S,2'S,3''S,4''S,2'''S)-1-{2'-[3''-(2'''-amino-3'''-tert-butoxy-propionylamino)-2''-oxo-4''-vinyl-piperidin-1''-yl]-6'-benzyloxycarbonylamino-hexanoyl}-pyrrolidine-2-carboxylic acid tert-butyl ester 
• 862473-29-8 (2S,2'S,3''S,4''S,2'''S)-1-{2'-[3''-(2'''-amino-3'''-benzyloxypropionylamino)-2''-oxo-4''-vinyl-piperidin-1''-yl]-6'-benzyloxycarbonylamino-hexanoyl}-pyrrolidine-2-carboxylic acid tert-butyl ester 
• 862473-35-6 (2S,2'S,3''S,4''S,2'''S)-1-{2'-[3''-(2'''-acetylamino-3'''-tert-butoxy-propionylamino)-2''-oxo-4''-vinyl-piperidin-1''-yl]-6'-benzyloxycarbonylamino-hexanoyl}-pyrrolidine-2-carboxylic acid tert-butyl ester 
• 862473-36-7 (3S,4R,2'S,1''S,2'''S)-3-(2'-acetylamino-3'-tert-butoxy-propionylamino)-1-[5''-benzyloxycarbonylamino-1''-(2'''-tert-butoxycarbonyl-pyrrolidine-1'''-carbonyl)-pentyl]-2-oxo-piperidine-4-carboxylic acid 
• 862473-30-1 (2S,2'S,3''S,4''S,2'''S)-1-{2'-[3''-(2'''-acetylamino-3'''-benzyloxy-propionylamino)-2''-oxo-4''-vinyl-piperidin-1''-yl]-6'-benzyloxycarbonylamino-hexanoyl}-pyrrolidine-2-carboxylic acid tert-butyl ester 
• 862473-28-7 (2S,2'S,3''S,4''S,2'''S)-1-{2'-[3''-(3'''-benzyloxy-2'''-tert-butoxycarbonylamino-propionylamino)-2''-oxo-4''-vinyl-piperidin-1''-yl]-6'-benzyloxycarbonylamino-hexanoyl}-pyrrolidine-2-carboxylic acid tert-butyl ester 
• 862473-33-4 (2S,2'S,3''S,4''S,2'''S)-1-(6'-benzyloxycarbonylamino-2'-{3''-[3'''-tert-butoxy-2'''-(9H-fluoren-9''''-ylmethoxycarbonylamino)-propionylamino]-2''-oxo-4''-vinyl-piperidin-1''-yl}-hexanoyl)-pyrrolidine-2-carboxylic acid tert-butyl ester 

Relevant articles and documents

Synthesis of 4-substituted-3-aminopiperidin-2-ones: Application to the synthesis of a conformationally constrained tetrapeptide N-acetyl-Ser-Asp-Lys- Pro

A new and practical synthetic strategy is developed for the synthesis of six-membered lactam-bridged dipeptides, 4-substituted-3-aminopiperidin-2-ones, featuring two key steps: (a) a diastereoselective addition of cuprate to (E)-α,β-unsaturated ester (3)