862647-49-2Relevant articles and documents
Inhibitors of lipoprotein(a) assembly
Sexton, Karen E.,Lee, Helen T.,Massa, Mark,Padia, Janak,Patt, William C.,Liao, Peggy,Pontrello, Jason K.,Roth, Bruce D.,Spahr, Mark A.,Ramharack, Randy
, p. 4827 - 4845 (2007/10/03)
Compounds of the general structure A and B were investigated for their activity as lipoprotein(a), [Lp(a)], assembly (coupling) inhibitors. SAR around the amino acid derivatives (structure A) gave compound 14-6 as a potent coupling inhibitor. Oral dosing