862686-09-7 Usage
General Description
4-(4-Acetyl-piperazin-1-yl)-2-methylaniline, also known as APMA, is a chemical compound that is commonly used as a precursor in the synthesis of pharmaceuticals. It is a piperazine derivative with an acetyl and methyl group attached to the piperazine ring, and an aniline group attached to the carbon. APMA is known to have potential biological activities and is being studied for its pharmacological properties, including as a potential anti-cancer agent. It is important to handle APMA with care as it is a potentially hazardous chemical that can cause skin and eye irritation, and may be harmful if ingested or inhaled.
Check Digit Verification of cas no
The CAS Registry Mumber 862686-09-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,2,6,8 and 6 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 862686-09:
(8*8)+(7*6)+(6*2)+(5*6)+(4*8)+(3*6)+(2*0)+(1*9)=207
207 % 10 = 7
So 862686-09-7 is a valid CAS Registry Number.
InChI:InChI=1/C13H19N3O/c1-10-9-12(3-4-13(10)14)16-7-5-15(6-8-16)11(2)17/h3-4,9H,5-8,14H2,1-2H3
862686-09-7Relevant articles and documents
Design, synthesis and SAR study of 2-aminopyrimidines with diverse Michael addition acceptors for chemically tuning the potency against EGFRL858R/T790M
Chen, Wenteng,Liu, Shuangrong,Liu, Xingyu,Pan, Youlu,Shao, Jiaan
, (2020/08/10)
The covalent binding nature of irreversible kinase inhibitors potentially increases the severity of “off-target” toxicity. Based on our continual strategy of chemically tuning the Michael addition acceptors, herein, we further explore the relationship amo
OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS
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Page/Page column 317, (2008/06/13)
Compounds of formula (I), and salts and pro-drugs thereof: Formula (I) wherein for example R1 is optionally substituted aryl or heteroaryl; Y is a linking group selected from, for example, a direct bond, and a (substituted) alkyl chain; R2