862907-10-6

Basic information

• Product Name: tert-butyl 3-benzyl-2-oxoindoline-1-carboxylate
• Synonyms: tert-butyl 3-benzyl-2-oxoindoline-1-carboxylate
• CAS NO: 862907-10-6
• Molecular Weight: 323.392
• Mol File: 862907-10-6.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: tert-butyl 3-benzyl-2-oxoindoline-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 3-benzyl-2-oxoindoline-1-carboxylate(862907-10-6)
• EPA Substance Registry System: tert-butyl 3-benzyl-2-oxoindoline-1-carboxylate(862907-10-6)

Safety Data

• Hazardous Substances Data: 862907-10-6(Hazardous Substances Data)

Upstream product

• 160858-75-3 1-tert-butoxycarbonylisatin 
• 1617519-37-5 C₂₀H₂₁NO₄ 
• 7511-08-2 3-benzyl-2-oxindole 
• 24424-99-5 di-tert-butyl dicarbonate 
• 91-56-5 indole-2,3-dione 
• 100-52-7 benzaldehyde 
• 3359-49-7 3-benzylideneoxindole 
• 59-48-3 2-oxoindole 
• 1589-82-8 phenylmagnesium bromide 
• 79419-75-3 3-benzyl-3-hydroxyindolin-2-one 

Downstream Products

• 1180583-34-9 C₃₁H₃₁NO₅ 
• 1207340-27-9 (S)-di-tert-butyl 1-(3-benzyl-1-(tert-butoxycarbonyl)-2-oxoindolin-3-yl)hydrazine-1,2-dicarboxylate 
• 1290607-33-8 (R)-tert-butyl 3-((S)-1-acetamido-2-nitroethyl)-3-benzyl-2-oxoindoline-1-carboxylate 
• 1402139-45-0 C₂₀H₂₀FNO₃ 
• 1262759-29-4 C₂₃H₂₅NO₃ 

Relevant articles and documents

Microfluidic Visible-Light Paternò–Büchi Reaction of Oxindole Enol Ethers

A novel microfluidic visible-light process for the functionalisation of oxindoles is reported. The chemistry is based on the reactivity of the corresponding enol ethers, which participate in a site-, regio- and diastereoselective [2+2] heterocycloaddition (Paternò–Büchi) process. The mild reaction conditions, the use of available ketones, together with the high generality (23 examples) and robustness (up to gram scale) make this process a useful synthetic platform for the construction of structurally strained heterocycles.

Chincona alkaloid-catalyzed enantioselective trifluoromethylthiolation of oxindoles

An organocatalytic asymmetric trifluoromethylthiolation of 3-aryl or 3-alkyloxindoles employing a trifluoromethyl-substituted thioperoxide as the electrophilic trifluoromethylthiolating reagent was described. Reactions occurred in good to excellent enanti

Phosphine-catalyzed enantioselective γ-addition of 3-substituted oxindoles to 2,3-butadienoates and 2-butynoates: Use of prochiral nucleophiles

The first phosphine-catalyzed enantioselective γ-addition with prochiral nucleophiles and 2,3-butadienoates as the reaction partners has been developed. Both 3-alkyl- and 3-aryl-substituted oxindoles could be employed in this process, which is catalyzed by a chiral phosphine that is derived from an amino acid, thus affording oxindoles that bear an all-carbon quaternary center at the 3-position in high yields and excellent enantioselectivity. The synthetic value of these γ-addition products was demonstrated by the formal total synthesis of two natural products and by the preparation of biologically relevant molecules and structural scaffolds.