863016-87-9Relevant articles and documents
An efficient [3+2] annulation for the asymmetric synthesis of densely-functionalized pyrrolidinones and γ-butenolides
Qian, Hui,Sun, Song,Zhao, Wanxiang,Sun, Jianwei
supporting information, p. 11295 - 11298 (2020/10/06)
Disclosed here is a new [3+2] annulation of siloxy alkynes that provides robust access to highly enantioenriched, densely-substituted pyrrolidinones and γ-butenolides, whose direct synthesis remains challenging. This process also represents a rare asymmetric synthesis of enantrioenriched molecules from siloxy alkynes.
Epoxy-annulations by reactions of α-amido ketones with vinyl sulfonium salts. Reagent versus substrate control and kinetic resolution
Unthank, Matthew G.,Tavassoli, Bahareh,Aggarwal, Varinder K.
supporting information; experimental part, p. 1501 - 1504 (2009/04/12)
(Chemical Equation Presented) Diphenyl vinyl sulfonium salt and chiral amido-ketones undergo highly diastereoselective epoxy-annulation reactions in good yield. The use of a chiral vinyl sulfonium salt dominates the stereochemical outcome of the annulatio
