86318-87-8

Basic information

• Product Name: (4-Methoxy-phenyl)-phosphoramidic acid (2R,3R,4R,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-(tetrahydro-furan-2-yloxy)-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester
• CAS NO: 86318-87-8
• Molecular Weight: 912.33
• Mol File: 86318-87-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4-Methoxy-phenyl)-phosphoramidic acid (2R,3R,4R,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-(tetrahydro-furan-2-yloxy)-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4-Methoxy-phenyl)-phosphoramidic acid (2R,3R,4R,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-(tetrahydro-furan-2-yloxy)-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester(86318-87-8)
• EPA Substance Registry System: (4-Methoxy-phenyl)-phosphoramidic acid (2R,3R,4R,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-(tetrahydro-furan-2-yloxy)-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester(86318-87-8)

Safety Data

• Hazardous Substances Data: 86318-87-8(Hazardous Substances Data)

Upstream product

• 86318-84-5 5'-O-dimethoxytrityl-2'-O-tetrahydrofuranyl uridine 
• 82556-11-4 o-chlorophenyl phosphoro-p-anisidochloridate 

Downstream Products

• 86318-91-4 2'-O-tetrahydrofuranyl-3'-(o-chlorophenyl)-p-anisidophosphoryluridine 

Relevant articles and documents

A NEW SOLID-PHASE SYNTHESIS OF RIBOOLIGONUCLEOTIDES USING THE 3'-PHOSPHORO-p-ANISIDATE PROTECTING GROUP FOR STEPWISE SYNTHESIS IN THE 3'-DIRECTION

A nonaribonucleotide CAGGUAAGU has been synthesized by the phosphotriester solid-phase method.The 5'-linked 2'-O-tetrahydrofuranyl-N-benzoylcytidine 3'-O-(o-chlorophenyl) phosphate was used as the starting material and chain was elongated in the 3'-direction by removal of the phosphoro-p-anisidate group using isoamyl nitrite under neutal conditions.Keywords - nonaribooligonucleotide; splice site RNA; phosphoro-p-anisidate method; isoamyl nitrite