86318-94-7

Basic information

• Product Name: (4-Methoxy-phenyl)-phosphoramidic acid 2-chloro-phenyl ester (2R,3R,4R,5R)-2-hydroxymethyl-5-(2-isobutyrylamino-6-oxo-1,6-dihydro-purin-9-yl)-4-(tetrahydro-furan-2-yloxy)-tetrahydro-furan-3-yl ester
• CAS NO: 86318-94-7
• Molecular Weight: 719.088
• Mol File: 86318-94-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4-Methoxy-phenyl)-phosphoramidic acid 2-chloro-phenyl ester (2R,3R,4R,5R)-2-hydroxymethyl-5-(2-isobutyrylamino-6-oxo-1,6-dihydro-purin-9-yl)-4-(tetrahydro-furan-2-yloxy)-tetrahydro-furan-3-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4-Methoxy-phenyl)-phosphoramidic acid 2-chloro-phenyl ester (2R,3R,4R,5R)-2-hydroxymethyl-5-(2-isobutyrylamino-6-oxo-1,6-dihydro-purin-9-yl)-4-(tetrahydro-furan-2-yloxy)-tetrahydro-furan-3-yl ester(86318-94-7)
• EPA Substance Registry System: (4-Methoxy-phenyl)-phosphoramidic acid 2-chloro-phenyl ester (2R,3R,4R,5R)-2-hydroxymethyl-5-(2-isobutyrylamino-6-oxo-1,6-dihydro-purin-9-yl)-4-(tetrahydro-furan-2-yloxy)-tetrahydro-furan-3-yl ester(86318-94-7)

Safety Data

• Hazardous Substances Data: 86318-94-7(Hazardous Substances Data)

Upstream product

• 82556-11-4 o-chlorophenyl phosphoro-p-anisidochloridate 
• 86327-76-6 5'-O-dimethoxytrityl-2'-O-tetrahydrofuranyl-N-isobutyrylguanosine 
• 86318-90-3 (4-Methoxy-phenyl)-phosphoramidic acid (2R,3R,4R,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(2-isobutyrylamino-6-oxo-1,6-dihydro-purin-9-yl)-4-(tetrahydro-furan-2-yloxy)-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester 

Relevant articles and documents

A NEW SOLID-PHASE SYNTHESIS OF RIBOOLIGONUCLEOTIDES USING THE 3'-PHOSPHORO-p-ANISIDATE PROTECTING GROUP FOR STEPWISE SYNTHESIS IN THE 3'-DIRECTION

A nonaribonucleotide CAGGUAAGU has been synthesized by the phosphotriester solid-phase method.The 5'-linked 2'-O-tetrahydrofuranyl-N-benzoylcytidine 3'-O-(o-chlorophenyl) phosphate was used as the starting material and chain was elongated in the 3'-direction by removal of the phosphoro-p-anisidate group using isoamyl nitrite under neutal conditions.Keywords - nonaribooligonucleotide; splice site RNA; phosphoro-p-anisidate method; isoamyl nitrite