86321-30-4

Basic information

• Product Name: (2E)-3-[3-(sulfooxy)phenyl]prop-2-enoic acid
• CAS NO: 86321-30-4
• Molecular Formula: C₉H₈O₆S
• Molecular Weight: 244.2212
• Mol File: 86321-30-4.mol
• Article Data: 1

Chemical Properties

• Density: 1.616g/cm³
• Refractive Index: 1.637
• CAS DataBase Reference: (2E)-3-[3-(sulfooxy)phenyl]prop-2-enoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-3-[3-(sulfooxy)phenyl]prop-2-enoic acid(86321-30-4)
• EPA Substance Registry System: (2E)-3-[3-(sulfooxy)phenyl]prop-2-enoic acid(86321-30-4)

Safety Data

• Hazardous Substances Data: 86321-30-4(Hazardous Substances Data)

Upstream product

• 14755-02-3 3-hydroxy-trans-cinnamic acid 
• 14755-02-3 3-hydroxycinnamic acid 

Relevant articles and documents

2-Hydroxy-substituted cinnamic acids and acetanilides are selective growth inhibitors of Mycobacterium tuberculosis

Selective chemical hits are required for feeding the initial discovery phase of the anti-tuberculosis therapeutics pipeline. These chemical entities should ideally target novel mechanisms of action in order to tackle drug resistance in Mycobacterium tuberculosis. In this work, hydroxycinnamic acid and acetamidophenol skeleta were employed for assessing the effects of constitutional isomerism on in vitro anti-TB activity. The whole cell evaluation of minimum inhibitory concentration values of different substituted cinnamic acids and acetamidophenols showed that the free ortho hydroxyl group conferred both potency and selectivity. Both 2-coumaric acid and 2-acetamidophenol showed minimum inhibitory concentration below 150 μM against M. tuberculosis H 37Rv and selectivity index higher than 30.