863578-46-5

Basic information

• Product Name: 2,4-bis(methoxymethoxy)phenylboronic acid
• Synonyms: 2,4-bis(methoxymethoxy)phenylboronic acid
• CAS NO: 863578-46-5
• Molecular Weight: 242.036
• Mol File: 863578-46-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2,4-bis(methoxymethoxy)phenylboronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-bis(methoxymethoxy)phenylboronic acid(863578-46-5)
• EPA Substance Registry System: 2,4-bis(methoxymethoxy)phenylboronic acid(863578-46-5)

Safety Data

• Hazardous Substances Data: 863578-46-5(Hazardous Substances Data)

Usage

General Description

The chemical 2,4-bis(methoxymethoxy)phenylboronic acid is a boronic acid compound that consists of a phenylboronic acid group with two methoxy groups attached to each of the para carbon atoms of the phenyl ring. It is commonly used as a building block in the synthesis of various pharmaceuticals and organic compounds. This chemical is known for its ability to form stable complexes with diols and other compounds, making it valuable in a variety of chemical reactions and processes. Its unique structure and reactivity make it a versatile tool in organic chemistry and drug discovery research. However, it is important to handle this chemical with care due to its potential reactivity and health hazards.

Upstream product

• 5419-55-6 Triisopropyl borate 
• 295788-93-1 1-bromo-2,4-bis(methoxymethoxy)benzene 
• 108-46-3 recorcinol 
• 57234-29-4 1,3-bis(methoxymethyl)resorcinol 
• 1344028-46-1 1-iodo-2,4-dimethoxymethoxybenzene 
• 6626-15-9 4-Bromoresorcinol 

Downstream Products

• 296763-91-2 3-[2,4-bis(methoxymethoxy)-phenyl]-2-cyclohexen-1-one 
• 704912-96-9 1-(2,4-bis-methoxymethoxy-phenyl)-3-(3-{4-[3-(2,4-bis-methoxymethoxy-phenyl)-3-oxo-propyl]-2-methoxy-phenoxy}-4-methoxymethoxy-phenyl)-propan-1-one 
• 1156-78-1 2',4',5,7-tetrahydroxyisoflavone 
• 98094-87-2 Lupinalbin A 
• 1344028-49-4 2',4',5,7-tetramethoxymethoxyisoflavone 
• 863578-48-7 2-(2,4-bismethoxymethoxyphenyl)-3-cyclohexyl-1-[2-(tetrahydropyran-2-yloxy)ethyl]-1H-indole-6-carboxylic acid methyl ester 
• 863578-47-6 2-(2,4-bismethoxymethoxyphenyl)-3-cyclohexyl-1H-indole-6-carboxylic acid methyl ester 

Relevant articles and documents

Enantioselective Total Synthesis of Natural Isoflavans: Asymmetric Transfer Hydrogenation/Deoxygenation of Isoflavanones with Dynamic Kinetic Resolution

A concise and highly enantioselective synthesis of structurally diverse isoflavans from a single chromone is described. The key transformation is a single-step conversion of racemic isoflavanones into virtually enantiopure isoflavans by domino asymmetric transfer hydrogenation/deoxygenation with dynamic kinetic resolution.

Total synthesis of the pyranocoumaronochromone lupinalbin H

The pyranocoumaronochromone lupinalbin H was synthesized in three major steps, which involved preparation of 2′-hydroxygenistein by the Suzuki-Miyaura reaction, followed by oxidative cyclodehydrogenation into lupinalbin A. The final step was the regiospec

Discovery of conformationally constrained tetracyclic compounds as potent hepatitis C virus NS5B RNA polymerase inhibitors

We report a new series of hepatitis C virus NS5B RNA polymerase inhibitors containing a conformationally constrained tetracyclic scaffold. SAR studies led to the identification of 6,7-dihydro-5H-benzo[5,6][1,4]diazepino[7,1-a]indoles (19 and 20) bearing a basic pendent group with high biochemical and cellular potencies. These compounds displayed a very small shift in cellular potency when the replicon assay was performed in the presence of human serum albumin.