863660-04-2

Basic information

• Product Name: 5-[(E)-3-((2R,6S)-6-Benzyloxymethyl-tetrahydro-pyran-2-yl)-propenyl]-2,2-dimethyl-benzo[1,3]dioxin-4-one
• Synonyms: 5-[(E)-3-((2R,6S)-6-Benzyloxymethyl-tetrahydro-pyran-2-yl)-propenyl]-2,2-dimethyl-benzo[1,3]dioxin-4-one
• CAS NO: 863660-04-2
• Molecular Weight: 422.521
• Mol File: 863660-04-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-[(E)-3-((2R,6S)-6-Benzyloxymethyl-tetrahydro-pyran-2-yl)-propenyl]-2,2-dimethyl-benzo[1,3]dioxin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[(E)-3-((2R,6S)-6-Benzyloxymethyl-tetrahydro-pyran-2-yl)-propenyl]-2,2-dimethyl-benzo[1,3]dioxin-4-one(863660-04-2)
• EPA Substance Registry System: 5-[(E)-3-((2R,6S)-6-Benzyloxymethyl-tetrahydro-pyran-2-yl)-propenyl]-2,2-dimethyl-benzo[1,3]dioxin-4-one(863660-04-2)

Safety Data

• Hazardous Substances Data: 863660-04-2(Hazardous Substances Data)

Upstream product

• 164014-40-8 2,2-dimethyl-5-trifluoromethylsulfonyloxy-4H-(1,3)benzodioxin-4-one 
• 154714-19-9 5-hydroxy-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-one 
• 303-07-1 2,6-Dihydroxybenzoic acid 
• 863660-12-2 (2S,6R)-2-Benzyloxymethyl-6-[(E)-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-allyl]-tetrahydro-pyran 
• 863660-01-9 ((2R,6S)-6-Benzyloxymethyl-tetrahydro-pyran-2-yl)-acetaldehyde 
• 863662-92-4 (-)-2-((2R,6S)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2-yl)ethanol 

Downstream Products

• 677707-87-8 2-[6-(2-benzyloxy-4-(tert-butyl-dimethyl-silanyloxy)-7-{6-[3-(2,2-dimethyl-4-oxo-4H-benzo[1,3]dioxin-5-yl)-propyl]-tetrahydro-pyran-2-yl}-5-methyl-heptyl)-tetrahydro-pyran-2-yl]-2-methyl-propionic acid 2-trimethylsilanyl-ethyl ester 
• 863660-52-0 2-Hydroxy-6-[3-((2S,6S)-6-vinyl-tetrahydro-pyran-2-yl)-propyl]-benzoic acid (1R,2S)-1-((S)-2-benzyloxy-3-{(2S,6R)-6-[1-methyl-1-(2-trimethylsilanyl-ethoxycarbonyl)-ethyl]-tetrahydro-pyran-2-yl}-propyl)-2-methyl-but-3-enyl ester 

Relevant articles and documents

Assignment of absolute configuration to SCH 351448 via total synthesis

(Chemical Equation Presented) The synthesis and absolute configuration of SCH 351448, an interesting ionophoric natural product, are reported herein. Mukaiyama aldol-Prins and segment-coupling Prins reactions were employed to construct the constituent tetrahydropyrans of SCH 351448. Efforts to assemble the C2-symmetric core of the natural product by a templated olefin metathesis strategy are described; however, a stepwise fragment assembly was ultimately utilized to complete the target molecule.