863908-08-1

Basic information

• Product Name: (3R,11aS)-3-phenyl-2,3,11,11a-tetrahydro[1,3]oxazolo[2,3-b][3]benzazepin-5(6H)-one
• Synonyms: (3R,11aS)-3-phenyl-2,3,11,11a-tetrahydro[1,3]oxazolo[2,3-b][3]benzazepin-5(6H)-one
• CAS NO: 863908-08-1
• Molecular Weight: 279.338
• Mol File: 863908-08-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (3R,11aS)-3-phenyl-2,3,11,11a-tetrahydro[1,3]oxazolo[2,3-b][3]benzazepin-5(6H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,11aS)-3-phenyl-2,3,11,11a-tetrahydro[1,3]oxazolo[2,3-b][3]benzazepin-5(6H)-one(863908-08-1)
• EPA Substance Registry System: (3R,11aS)-3-phenyl-2,3,11,11a-tetrahydro[1,3]oxazolo[2,3-b][3]benzazepin-5(6H)-one(863908-08-1)

Safety Data

• Hazardous Substances Data: 863908-08-1(Hazardous Substances Data)

Upstream product

• 4406-80-8 1,5-dihydro-3-benzoxepine-2,4-dione 
• 7500-53-0 1,2-Phenylenediacetic acid 
• 863908-15-0 methyl (R)-2-<2-{N-[1-phenyl-2-(triisopropylsilyloxy)ethyl]carbamoylmethyl}phenyl>acetate 
• 863908-17-2 (R)-2-[2-(2-hydroxyethyl)phenyl]-N-[1-phenyl-2-(triisopropylsilyloxy)ethyl]acetamide 
• 863908-18-3 (R)-2-[2-(formylmethyl)phenyl]-N-[1-phenyl-2-(triisopropylsilyloxy)ethyl]acetamide 
• 863908-11-6 (R)-2-{[N-(2-hydroxy-1-phenylethyl)carbamoylmethyl]phenyl}acetic acid 
• 863908-13-8 methyl (R)-2-{2-[N-(2-hydroxy-1-phenylethyl)carbamoylmethyl]phenyl}acetate 
• 929297-14-3 (R)-2-[2-(2,2-dimethoxyethyl)phenyl]-N-(2-hydroxy-1-phenylethyl)acetamide 
• 863908-20-7 2-[2-(2,2-dimethoxy-ethyl)-phenyl]-N-(1-phenyl-2-triisopropylsilanyloxy-ethyl)-acetamide 

Downstream Products

• 929297-20-1 (3R,6R,11aS)-6-phenethyl-3-phenyl-2,3,11,11a-tetrahydro[1,3]oxazolo[2,3-b][3]benzazepin-5(6H)-one 
• 929297-24-5 (3R,6R,11aS)-6-(2-methylbenzyl)-3-phenyl-2,3,11,11a-tetrahydro[1,3]oxazolo[2,3-b][3]benzazepin-5(6H)-one 
• 929297-28-9 (3R,6R,11aS)-6-(4-methoxybenzyl)-3-phenyl-2,3,11,11a-tetrahydro[1,3]oxazolo[2,3-b][3]benzazepin-5(6H)-one 
• 929297-32-5 (3R,6R,11aS)-6-methyl-3-phenyl-2,3,11,11a-tetrahydro[1,3]oxazolo[2,3-b][3]benzazepin-5(6H)-one 
• 929297-36-9 (2R)-2-[(1R)-1-benzyl-2,3,4,5-tetrahydro-1H-3-benzazepin-3-yl]-2-phenylethan-1-ol 
• 929297-40-5 (2R)-2-[(1R)-1-(2-methylbenzyl)-2,3,4,5-tetrahydro-1H-3-benzazepin-3-yl]-2-phenylethan-1-ol 
• 929297-42-7 (2R)-2-[(1R)-1-(4-methoxybenzyl)-2,3,4,5-tetrahydro-1H-3-benzazepin-3-yl]-2-phenylethan-1-ol 
• 929297-44-9 (2R)-2-[(1R)-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepin-3-yl]-2-phenylethan-1-ol 
• 863908-22-9 (3R,6R,11aS)-6-benzyl-3-phenyl-2,3,11,11a-tetrahydro[1,3]oxazolo[2,3-b][3]benzazepin-5(6H)-one 

Relevant articles and documents

Asymmetric synthesis of 1-substituted tetrahydro-3-benzazepines as NMDA receptor antagonists

A novel asymmetric synthesis of 1-substituted tetrahydro-3-benzazepines (R)-15 and (S)-15 has been performed. Starting with o-phenylenediacetic acid (1) and (R)-phenylglycinol as chiral auxiliary the tricyclic oxazololactam (3R)-10 was synthesized as key