863969-69-1Relevant articles and documents
Use of isopropyl alcohol as a solvent in Ti(O-i-Pr)4-catalyzed Kn?evenagel reactions
Yamashita, Kohei,Tanaka, Takanori,Hayashi, Masahiko
, p. 7981 - 7985 (2005)
Kn?evenagel reactions of aldehydes and ketones with malononitrile, isopropyl cyanoacetate and diisopropyl malonate catalyzed by Ti(O-i-Pr) 4 proceeded smoothly in i-PrOH to give the corresponding reaction products in good to high yield. 3-Substituted coumarins were prepared by the present method.