863990-91-4

Basic information

• Product Name: 2-(4-methoxybenzyloxy)-1,3-dioxoisoindoline-5-carboxylic acid
• Synonyms: 2-(4-methoxybenzyloxy)-1,3-dioxoisoindoline-5-carboxylic acid
• CAS NO: 863990-91-4
• Molecular Weight: 327.293
• Mol File: 863990-91-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-methoxybenzyloxy)-1,3-dioxoisoindoline-5-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methoxybenzyloxy)-1,3-dioxoisoindoline-5-carboxylic acid(863990-91-4)
• EPA Substance Registry System: 2-(4-methoxybenzyloxy)-1,3-dioxoisoindoline-5-carboxylic acid(863990-91-4)

Safety Data

• Hazardous Substances Data: 863990-91-4(Hazardous Substances Data)

Upstream product

• 552-30-7 trimellitic Anhydride 

Downstream Products

• 863990-95-8 2-hydroxy-1,3-dioxo-N-(4-(prop-2-ynyloxy)phenethyl)isoindoline-5-carboxamide 
• 863990-94-7 2-(4-methoxybenzyloxy)-1,3-dioxo-N-(4-(prop-2-ynyloxy)phenethyl)isoindoline-5-carboxamide 

Relevant articles and documents

A new supported reagent for the parallel synthesis of primary and secondary O-alkyl hydroxylamines through a base-catalyzed Mitsunobu reaction

The growing field of applications of O-alkyl hydroxylamines in medicinal chemistry and chemical biology has motivated the search for a parallel synthesis. A solid-phase approach based on the alkylation by alcohols of a new supported N-hydroxyphthalimide reagent using a Mitsunobu reaction followed by methylaminolysis has been optimized. This study points out the importance of the linker and a specific base effect for the Mitsunobu reaction. A large variety of alcohols can be used to give with moderate to high yields diverse O-alkyl hydroxylamines in high purity.