86402-00-8

Basic information

• Product Name: (E)-N-tert-butyl-1-(4-chlorophenyl)methanimine
• Synonyms: (E)-N-tert-butyl-1-(4-chlorophenyl)methanimine
• CAS NO: 86402-00-8
• Molecular Weight: 195.692
• Mol File: 86402-00-8.mol
• Article Data: 21

Chemical Properties

• CAS DataBase Reference: (E)-N-tert-butyl-1-(4-chlorophenyl)methanimine(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-N-tert-butyl-1-(4-chlorophenyl)methanimine(86402-00-8)
• EPA Substance Registry System: (E)-N-tert-butyl-1-(4-chlorophenyl)methanimine(86402-00-8)

Safety Data

• Hazardous Substances Data: 86402-00-8(Hazardous Substances Data)

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 75-64-9 tert-butylamine 
• 46234-01-9 N-(4′-chlorobenzyl)-2-methylpropan-2-amine 
• 637-87-6 1-Chloro-4-iodobenzene 
• 119072-55-8 tert-butylisonitrile 
• 104-83-6 1-Chloro-4-(chloromethyl)benzene 
• 104-86-9 4-chlorobenzylamine 

Downstream Products

• 153164-03-5 (E)-7-p-chlorobenzylidene-2H,6H-naphtho<1,8-b,c>furan-2,6-dione 
• 42498-40-8 N-tert-butyl-4-chlorobenzamide 
• 46234-01-9 N-(4′-chlorobenzyl)-2-methylpropan-2-amine 
• 23898-60-4 2-tert-butyl-3-(p-chlorophenyl)oxaziridine 
• 1246633-36-2 4-chloro-2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)benzaldehyde 
• 1112209-14-9 C₁₃H₁₆BClO₃ 
• 104-88-1 4-chlorobenzaldehyde 
• 82632-44-8 [1-[4-Chloro-2-((E)-styryl)-phenyl]-meth-(E)-ylidene]-methyl-amine 
• 120347-64-0 5-chloro-2-(N-t-methyliminomethyl)-trans-stilbene 
• 82632-49-3 7-chloro-2-methyl-3-phenylisoquinolin-1(2H)-one 
• 40117-30-4 N-<(4-Chlorophenyl)methylene>-2-methyl-2-propanamine N-Oxide 
• 82044-40-4 (2R,3R)-2-tert-Butyl-3-(4-chloro-phenyl)-oxaziridine 
• 40117-30-4 (Z)?N?(tert?butyl)?1?(4?chlorophenyl)methanimine oxide 

Relevant articles and documents

Photocatalytic aerobic oxidation of amines to imines on BiVO4 under visible light irradiation

BiVO4 was found to be an efficient photocatalyst under visible light irradiation for selective oxidation of amines to imines with high activity (99% conversion) and selectivity (up to 99%) using oxygen as an oxidant.

Convenient fabrication of carbon doped WO3?x ultrathin nanosheets for photocatalytic aerobic oxidation of amines

It is an important chemical transformation for oxidation of amines to imines, on account of very important versatile applications of imines in organic synthesis. Here, we develop a convenient way to synthesize carbon doped WO3?x ultrathin nanos

Luminescent ruffled iridium(iii) porphyrin complexes containing N-heterocyclic carbene ligands: structures, spectroscopies and potent antitumor activities under dark and light irradiation conditions

A panel of iridium(iii) porphyrin complexes containing axial N-heterocyclic carbene (NHC) ligand(s) were synthesized and characterized. X-ray crystal structures of the bis-NHC complexes [IrIII(ttp)(IMe)2]+ (2a), [IrIII(oep)(BIMe)2]+ (2d), [IrIII(oep)(IiPr)2]+ (2e) and [IrIII(F20tpp)(IMe)2]+ (2f) display ruffled porphyrin rings with mesocarbon displacements of 0.483-0.594 ? and long Ir-CNHC bonds of 2.100-2.152 ?. Variable-temperature 1H NMR analysis of 2a reveals that the macrocycle porphyrin ring inversion takes place in solution with an activation barrier of 40 ± 1 kJ mol?1. The UV-vis absorption spectra of IrIII(por)-NHC complexes display split Soret bands. TD-DFT calculations and resonance Raman experiments show that the higher-energy Soret band is derived from the 1MLCT dπ(Ir) → π*(por) transition. The near-infrared phosphorescence of IrIII(por)-NHC complexes from the porphyrin-based 3(π, π*) state features broad emission bands at 701-754 nm with low emission quantum yields and short lifetimes (Φem III(por)(IMe)2]+ complexes (por = ttp and oep) are efficient photosensitizers for 1O2 generation (Φso = 0.64 and 0.88) and are catalytically active in the light-induced aerobic oxidation of secondary amines and arylboronic acid. The bis-NHC complexes exhibit potent dark cytotoxicity towards a panel of cancer cells with IC50 values at submicromolar levels. The cytotoxicity of these complexes could be further enhanced upon light irradiation with IC50 values as low as nanomolar levels in association with the light-induced generation of reactive oxygen species (ROS). Bioimaging of [IrIII(oep)(IMe)2]+ (2c) treated cells indicates that this Ir complex mainly targets the endoplasmic reticulum. [IrIII(oep)(IMe)2]+ catalyzes the photoinduced generation of singlet oxygen and triggers protein oxidation, cell cycle arrest, apoptosis and the inhibition of angiogenesis. It also causes pronounced photoinduced inhibition of tumor growth in a mouse model of human cancer.