864383-28-8

Basic information

• Product Name: 1,3,5-tris-(2-(3-(t-butoxycarbonyl)propylmalonyl)ethoxymethyl)benzene
• Synonyms: 1,3,5-tris-(2-(3-(t-butoxycarbonyl)propylmalonyl)ethoxymethyl)benzene
• CAS NO: 864383-28-8
• Molecular Weight: 985.087
• Mol File: 864383-28-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1,3,5-tris-(2-(3-(t-butoxycarbonyl)propylmalonyl)ethoxymethyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,5-tris-(2-(3-(t-butoxycarbonyl)propylmalonyl)ethoxymethyl)benzene(864383-28-8)
• EPA Substance Registry System: 1,3,5-tris-(2-(3-(t-butoxycarbonyl)propylmalonyl)ethoxymethyl)benzene(864383-28-8)

Safety Data

• Hazardous Substances Data: 864383-28-8(Hazardous Substances Data)

Upstream product

• 611212-49-8 4-(benzyloxy)butanoic acid t-butyl ester 
• 864383-26-6 2-{[3-(tert-butoxycarbonyl)propoxy]carbonyl}acetic acid 
• 152065-61-7 1,3,5-tris-((2'-hydroxy)ethoxymethyl)benzene 
• 152065-57-1 1,3,5-tris(4'-hydroxy-2'-oxa-1'-butyl)benzene tri(2'-tetrahydropyranyl) ether 
• 2672-58-4 1,3,5-tris-(methoxycarbonyl)benzene 
• 554-95-0 benzene-1,3,5-tricarboxylic acid 
• 4464-18-0 1,3,5-tris(hydroxymethyl)benzene 
• 59854-12-5 tert-butyl 4-hydroxybutyrate 

Relevant articles and documents

Synthesis and orthogonal functionalization of [60]fullerene e,e,e-trisadducts with two spherically defined addend zones

e,e,e-Trisadducts 13 and 15 have been prepared by a highly regioselective threefold cyclopropanation of tripodal malonates 10 and 12 with C60. The yield and regioselectivity depend on the length and structure of the tethers that connect the malonate units to the focal benzene core of 13-15. As a consequence of the template-directed synthesis, all ce.e-trisadducts were formed as in/out isomers exclusively and contain two spherically well-defined addend zones with equatorial and polar orientation, respectively. By variation of the outer malonate termini of the tethers, selective functionalization of the equatorial addend zone could be achieved, thus leading to fine-tuning of intermolecular interactions, such as solubility or aggregation phenomena. After removal of the focal benzene moiety in 14 and 15, selective functionalization of the polar addend zone could be achieved. Strong intramolecular hydrogen-bonding networks of the polar substituents in the polar addend zone could be observed by 1H NMR spectroscopic analysis. By orthogonal functionalization of both addend zones, fullerene derivatives 44-48 could be synthesized as one single in/out isomer, thus greatly enhancing the potential of e,e,e-trisadducts as building blocks in supramolecular architectures.

Method of synthesis of water soluble fullerene polyacids using a malonate reactant

In one embodiment, the present invention is directed to a method for synthesizing compounds of the formula where Cm is a fullerene having m carbon atoms, the method comprising the steps of forming a linear malonate compound of the formula where each Z is the same or different and is a straight-chain or branched-chain aliphatic radical having from 1-30 carbon atoms which may be unsubstituted or monosubstituted or polysubstituted by identical or different substitutents, in which radicals up to every third —CH2— unit can be replaced by O or NR″, n is an integer from 2 to 10, and the unfilled valences of the first and nth malonate groups are filled with bonds to hydrogen, a hydrocarbon group or substituted hydrocarbon group having 1-20 carbon atoms, or a chain containing unsubstituted or substituted aryl or other cyclic groups; or (ii) a branched malonate compound of the formula where Z′ is an aliphatic radical having from 1-30 carbon atoms which may be unsubstituted or monosubstituted or polysubstituted by identical or different substitutents, in which radicals up to every third —CH2— unit can be replaced by O or NR″; and n is an integer from 2 to 10; reacting said malonate compound with Cm to form an adduct of the formula each Z is bonded to both one carboxylate group of a first malonate moiety and one carboxylate group of a second malonate moiety and the unfilled valences of the first and nth malonate groups are filled with bonds to hydrogen, a hydrocarbon group or substituted hydrocarbon group having 1-20 carbon atoms, or a chain containing unsubstituted or substituted aryl or other cyclic groups; and hydrolyzing said adduct to form the compound.