864539-96-8

Basic information

• Product Name: 4-bromo-2-methyl-6-(trifluoromethyl)aniline
• Synonyms: 4-bromo-2-methyl-6-(trifluoromethyl)aniline
• CAS NO: 864539-96-8
• Molecular Weight: 254.049
• Mol File: 864539-96-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-bromo-2-methyl-6-(trifluoromethyl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-2-methyl-6-(trifluoromethyl)aniline(864539-96-8)
• EPA Substance Registry System: 4-bromo-2-methyl-6-(trifluoromethyl)aniline(864539-96-8)

Safety Data

• Hazardous Substances Data: 864539-96-8(Hazardous Substances Data)

Upstream product

• 92891-23-1 2-nitro-3-trifluoromethyl-toluene 
• 88301-98-8 2-methyl-6-(trifluoromethyl)aniline 

Downstream Products

• 910575-86-9 4-(2-oxo-1,2,4,5-tetrahydro-benzo[d][1,3]diazepin-3-yl)-piperidine-1-carboxylic acid (R)-2-(4-amino-3-methyl-5-trifluoromethyl-phenyl)-1-carboxy-ethyl ester 
• 910575-85-8 4-(2-oxo-1,2,4,5-tetrahydro-benzo[d][1,3]diazepin-3-yl)-piperidine-1-carboxylic acid (R)-2-(4-amino-3-methyl-5-trifluoromethyl-phenyl)-1-methoxycarbonyl-ethyl ester 
• 910575-83-6 (R)-3-(4-amino-3-methyl-5-trifluoromethyl-phenyl)-2-hydroxy-propionic acid 
• 910575-84-7 (R)-3-(4-amino-3-methyl-5-trifluoromethyl-phenyl)-2-hydroxy-propionic acid methyl ester 
• 910575-82-5 3-(4-amino-3-methyl-5-trifluoromethyl-phenyl)-2-oxo-propionic acid 
• 1374258-43-1 5-bromo-7-(trifluoromethyl)-1H-indazole 
• 1374258-44-2 methyl 7-(trifluoromethyl)-1H-indazole-5-carboxylate 
• 910575-81-4 (Z,E)-2-acetylamino-3-(4-amino-3-methyl-5-trifluoromethyl-phenyl)-acrylic acid methyl ester 

Relevant articles and documents

ARYL, HETEROARY, AND HETEROCYCLIC PHARMACEUTICAL COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS

Complement Factor D inhibitors, pharmaceutical compositions, and uses thereof, as well as processes for their manufacture are provided. The compounds provided include Formula I, Formula II, Formula III, Formula IV, and Formula V, or a pharmaceutically acceptable salt, prodrug, isotopic analog, N-oxide, or isolated isomer thereof, optionally in a pharmaceutically acceptable composition. The inhibitors described herein target Factor D and inhibit or regulate the complement cascade.

CGRP ANTAGONISTS, METHOD FOR THE PRODUCTION THEREOF, AND THEIR USE AS MEDICAMENTS

The invention relates to CGRP antagonists of general formula (I) in which: R1, R2, R3, R4 and X are defined as in Claim 1, to their tautomers, isomers, diastereomers, enantiomers, hydrates, mixtures and salts as well as the hydrates of the salts, in particular, their physiologically compatible salts with inorganic or organic acids and bases, and those compounds of general formula (I) in which one or more hydrogen atoms are replaced by deuterium. The invention also relates to medicaments containing these compounds, the use thereof, and to methods for producing them.