864658-69-5

Basic information

• Product Name: (R)-1-[(1R,2S)-2-((R)-2-Benzyloxy-dodec-4-ynyloxy)-cyclopentyloxy]-5-trimethylsilanyl-pent-4-yn-2-ol
• Synonyms: (R)-1-[(1R,2S)-2-((R)-2-Benzyloxy-dodec-4-ynyloxy)-cyclopentyloxy]-5-trimethylsilanyl-pent-4-yn-2-ol
• CAS NO: 864658-69-5
• Molecular Weight: 526.832
• Mol File: 864658-69-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-1-[(1R,2S)-2-((R)-2-Benzyloxy-dodec-4-ynyloxy)-cyclopentyloxy]-5-trimethylsilanyl-pent-4-yn-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-[(1R,2S)-2-((R)-2-Benzyloxy-dodec-4-ynyloxy)-cyclopentyloxy]-5-trimethylsilanyl-pent-4-yn-2-ol(864658-69-5)
• EPA Substance Registry System: (R)-1-[(1R,2S)-2-((R)-2-Benzyloxy-dodec-4-ynyloxy)-cyclopentyloxy]-5-trimethylsilanyl-pent-4-yn-2-ol(864658-69-5)

Safety Data

• Hazardous Substances Data: 864658-69-5(Hazardous Substances Data)

Upstream product

• 5057-99-8 trans-cyclopentane-1,2-diol 
• 26620-22-4 (+/-)-trans-1,2-diacetoxycyclopentane 
• 100-39-0 benzyl bromide 
• 20520-67-6 (1R,2R)-2-hydroxycyclopentyl acetate 
• 864658-76-4 [(R)-1-((1S,2R)-2-Methoxymethoxy-cyclopentyloxymethyl)-undec-3-ynyloxymethyl]-benzene 
• 864658-65-1 (R)-2-((1S,2R)-2-Methoxymethoxy-cyclopentyloxymethyl)-oxirane 
• 864658-73-1 Acetic acid (1R,2R)-2-methoxymethoxy-cyclopentyl ester 
• 864658-75-3 (1S,2R)-2-Methoxymethoxy-cyclopentanol 
• 241147-40-0 (1R,2R)-2-Methoxymethoxy-cyclopentanol 
• 864658-68-4 (R)-2-[(1R,2S)-2-((R)-2-Benzyloxy-dodec-4-ynyloxy)-cyclopentyloxymethyl]-oxirane 
• 1066-54-2 trimethylsilylacetylene 
• 864658-67-3 (1R,2S)-2-((R)-2-Benzyloxy-dodec-4-ynyloxy)-cyclopentanol 
• 864658-66-2 (R)-1-((1S,2R)-2-Methoxymethoxy-cyclopentyloxy)-dodec-4-yn-2-ol 

Relevant articles and documents

Synthesis of non-THF analogs of acetogenin toward simplified mimics

Acetogenin analogs in which the bis-adjacent THF ring was replaced with an enantioselectively synthesized 1,2-cyclopentanediol bis-ether skeleton were synthesized to obtain simplified mimics, and their inhibitory effect on mitochondrial NADH-ubiquinone oxidoreductase (complex I) was examined. The results clearly demonstrate that the 1,2-cyclopentanediol bis-ether motif can substitute for the bis-THF ring while maintaining very potent inhibitory activity at the nanomolar level.