864771-17-5

Basic information

• Product Name: 3-METHYL-5-PINACOLATOBORYL-INDAZOLE
• Synonyms: 3-METHYL-5-PINACOLATOBORYL-INDAZOLE;3-METHYL-5-PINALATOBORNYL-INDAZOLE;3-METHYL-5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-INDAZOLE;3-Methyl-1H-indazole-5-bonic acid pinacol ester;3-Methylindazole-5-boronic acid pinacol ester;3-Methyl-5-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole;1H-Indazole, 3-Methyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-;3-hydroxy-2,3-dimethylbutan-2-yl 3-methyl-1H-indazole-5-carboxylate
• CAS NO: 864771-17-5
• Molecular Formula: C₁₄H₁₉BN₂O₂
• Molecular Weight: 258.12
• Product Categories: Indazole;Organic boronic acid
• Mol File: 864771-17-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 416.7 °C at 760 mmHg
• Flash Point: 205.8 °C
• Appearance: /
• Density: 1.13 g/cm³
• Vapor Pressure: 9.03E-07mmHg at 25°C
• Refractive Index: 1.558
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-METHYL-5-PINACOLATOBORYL-INDAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHYL-5-PINACOLATOBORYL-INDAZOLE(864771-17-5)
• EPA Substance Registry System: 3-METHYL-5-PINACOLATOBORYL-INDAZOLE(864771-17-5)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45
• RIDADR: UN2811
• Hazardous Substances Data: 864771-17-5(Hazardous Substances Data)

Usage

General Description

3-Methyl-5-pinacolatoboryl-indazole is a chemical compound that belongs to the class of indazoles, which are heterocyclic molecules containing a five-membered ring with two nitrogen atoms. This particular compound features a boron atom attached to the indazole moiety, making it a boron-containing indazole derivative. It is commonly used as a versatile building block for the synthesis of various organic compounds, particularly in the fields of medicinal chemistry and materials science. Its unique structure and reactivity make it valuable in the development of new drugs and materials with potential applications in pharmaceuticals, agrochemicals, and advanced materials.

InChI:InChI=1/C14H19BN2O2/c1-9-11-8-10(6-7-12(11)17-16-9)15-18-13(2,3)14(4,5)19-15/h6-8H,1-5H3,(H,16,17)

Upstream product

• 552331-16-5 5-bromo-3-methyl-1H-indazole 
• 73183-34-3 bis(pinacol)diborane 
• 45762-41-2 4-bromo-2-ethylaniline 
• 76-09-5 2,3-dimethyl-2,3-butane diol 
• 1245816-25-4 (3-methyl-1H-indazol-5-yl)boronic acid 

Downstream Products

• 864775-90-6 2-fluoro-6-(3-methyl-1H-indazol-5-yl)-4-nitrophenol 
• 1613639-35-2 N-{(R)-2-[5-(3-methyl-1H-indazol-5-yl)pyridin-3-ylamino]-2-phenylethyl}benzamide 
• 1613639-20-5 (R)-2-[5-(3-methyl-1H-indazol-5-yl)pyridin-3-ylamino]-2-phenylacetamide 
• 1613639-21-6 (S)-2-[5-(3-methyl-1H-indazol-5-yl)pyridin-3-ylamino]-2-phenylacetamide 
• 1613639-31-8 (R)-N²-(2-methoxyethyl)-N¹-[5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl]-1-phenylethane-1,2-diamine 
• 1220696-53-6 1,3-dimethyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indazole 

Relevant articles and documents

IMIDAZOPYRIDINES AND IMIDAZOPYRAZINES AS LSD1 INHIBITORS

The present invention is directed to imidazo[1,5-a]pyridine and imidazo[1,5-a]pyrazine derivatives which are LSD1 inhibitors useful in the treatment of diseases such as cancer.

NOVEL BI-RING PHENYL-PYRIDINES/PYRAZINES FOR THE TREATMENT OF CANCER

The invention provides novel compounds having the general formula: wherein R1, R2 and R3 are as described herein, compositions including the compounds and methods of using the compounds.

NOVEL IMIDAZOTHIAZOLES AND IMIDAZOXAZOLES

The present invention is directed to novel compounds of formula (I) wherein the variables are as defined herein. The compounds of formula (I) are useful as kinase inhibitors and as such would be useful in treating certain conditions and diseases, especially inflammatory conditions and diseases and proliferative disorders and conditions, for example, cancers.