864866-47-7

Basic information

• Product Name: 5-Bromo-2-isopropyl-2,3-dihydro-isoindol-1-one
• Synonyms: 5-Bromo-2-isopropyl-2,3-dihydro-isoindol-1-one
• CAS NO: 864866-47-7
• Molecular Formula: C₁₁H₁₂BrNO
• Molecular Weight: 254.12308
• Mol File: 864866-47-7.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-Bromo-2-isopropyl-2,3-dihydro-isoindol-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Bromo-2-isopropyl-2,3-dihydro-isoindol-1-one(864866-47-7)
• EPA Substance Registry System: 5-Bromo-2-isopropyl-2,3-dihydro-isoindol-1-one(864866-47-7)

Safety Data

• Hazardous Substances Data: 864866-47-7(Hazardous Substances Data)

Upstream product

• 888030-75-9 N-isopropyl-4-bromo-2-hydroxymethylbenzamide 
• 64169-34-2 5-bromophthalide 
• 75-31-0 isopropylamine 
• 888030-82-8 (5-bromo-3H-isobenzofuran-1-ylidene)-isopropyl-amine 
• 78471-43-9 methyl 4-bromo-2-(bromomethyl)benzoate 
• 68837-59-2 4-bromo-2-methylbenzoic acid 
• 99548-55-7 4-bromo-2-methyl-benzoic acid methyl ester 

Downstream Products

• 1295301-37-9 1-(4-(2-isopropyl-1-oxoisoindolin-5-yl)benzyl)-3-methylimidazolidine-2,4-dione 

Relevant articles and documents

Efficient synthesis of 1,4-diaryl-5-methyl-1,2,3-triazole, a potential mglur1 antagonist, and the risk assessment study of arylazides

A concise and practical synthesis of a 1,4-diaryl-5-methyl-1,2,3-triazole is described. A mGluR1 antagonist 1 was prepared with one-pot operation by the Negishi coupling reaction between two building blocks, 5-bromophthalimidine (2) and 1-aryl-5-methyl-4-

Fused Pyrazoles as FGFR Inhibitors

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DIARYL-SUBSTITUTED FIVE-MEMBERED HETEROCYCLE DERIVATIVE

The present invention provides the compounds represented by formula (I): (I) or pharmaceutical salts thereof, wherein: X 1 represents oxygen atoms and the like, X 2 represents nitrogen atoms and the like, X 3 represents nitrogen atoms and the like, X 4 represents nitrogen atoms and the like, R 1 represents formula (II-1): wherein X 5 represents sulfur atoms and the like, A 1 represents carbon atoms and the like, A 2 represents nitrogen atoms and the like and A ring represents phenyl group and the like, having mGluR1 inhibiting effect, and being usefull for preventing or treating convulsion, acute pain, inflammatory pain, chronic pain, brain disorder such as cerebral infarction or transient ischemick attack, psychotic disorder such as schizophrenia, anxiety, drug dependence, Parkinson's disease, or gastrointestinal disorder.