86490-71-3

Basic information

• Product Name: N-(4-benzoylphenyl)formamide
• CAS NO: 86490-71-3
• Molecular Formula: C₁₄H₁₁NO₂
• Molecular Weight: 225.2426
• Mol File: 86490-71-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 442.941°C at 760 mmHg
• Flash Point: 186.795°C
• Density: 1.222g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.633
• CAS DataBase Reference: N-(4-benzoylphenyl)formamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-benzoylphenyl)formamide(86490-71-3)
• EPA Substance Registry System: N-(4-benzoylphenyl)formamide(86490-71-3)

Safety Data

• Hazardous Substances Data: 86490-71-3(Hazardous Substances Data)

Upstream product

• 201230-82-2 carbon monoxide 
• 1144-74-7 4-nitrobenzophenone 
• 124-41-4 sodium methylate 
• 1137-41-3 (4-aminophenyl)(phenyl)methanone 
• 2258-42-6 formyl acetic anhydride 
• 122-51-0 orthoformic acid triethyl ester 
• 64-18-6 formic acid 

Downstream Products

• 3128-83-4 (4-isocyanophenyl)(phenyl)methanone 

Relevant articles and documents

Iridium-Catalysed Reductive Deoxygenation of Ketones with Formic Acid as Traceless Hydride Donor

An iridium-catalysed deoxygenation of ketones and aldehydes is achieved, with formic acid as hydride donor and water as co-solvent. At low catalyst loading, a number of 4-(N,N-disubstituted amino) aryl ketones are readily deoxygenated in excellent yields and chemoselectivity. Numerous functional groups, especially phenolic and alcoholic hydroxyls, secondary amine, carboxylic acid, and alkyl chloride, are well tolerable. Geminally dideuterated alkanes are obtained with up to 90% D incorporation, when DCO2D and D2O are used in place of their hydrogenative counterparts. The activating 4-(N,N-disubstituted amino)aryl groups have been demonstrated to undergo a variety of useful transformations. The deoxygenative deuterations have been used to prepare a deuterated drug molecule Chlorambucil-4,4-d2. (Figure presented.).

Silver-Catalyzed Chemoselective [4+2] Annulation of Two Isocyanides: A General Route to Pyridone-Fused Carbo- and Heterocycles

A silver-catalyzed chemoselective [4+2] annulation of aryl and heteroaryl isocyanides with α-substituted isocyanoacetamides was developed for the facile and efficient synthesis of 2-aminoquinolones, naphthyridines, and phenanthrolines. A mechanism for this multistep domino reaction is proposed on the basis of a13C-labeling experiment, according to which an unprecedented chemoselective heterodimerization of two different isocyanides generates an α-amidoketenimine intermediate, which undergoes 1,3-amino migration to form an α-imidoylketene, followed by 6 π electrocyclization.

Photoaffinity-labeled peptoids and depsipeptides by multicomponent reactions

Photoaffinity tags can be incorporated easily into peptoids and congeners by the Ugi and Passerini multicomponent reactions. Products related to photo-methionine and photo-leucine can be accomplished by diazirine-containing building blocks. The same proto