865483-45-0

Basic information

• Product Name: C₁₇H₂₁N₃O₅S₂
• CAS NO: 865483-45-0
• Molecular Weight: 411.503
• Mol File: 865483-45-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₇H₂₁N₃O₅S₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₂₁N₃O₅S₂(865483-45-0)
• EPA Substance Registry System: C₁₇H₂₁N₃O₅S₂(865483-45-0)

Safety Data

• Hazardous Substances Data: 865483-45-0(Hazardous Substances Data)

Upstream product

• 14988-21-7 4-(acetylamino)-3-methylbenzenesulfonyl chloride 
• 35303-76-5 4-(2-aminoethyl)benzenesulfonamide 

Downstream Products

• 871944-90-0 C₂₅H₃₄N₄O₆S₂ 

Relevant articles and documents

Synthesis and biological evaluation of sulfonylurea and thiourea derivatives substituted with benzenesulfonamide groups as potential hypoglycemic agents

A novel class of sulfonylurea and thiourea derivatives substituted with benzenesulfonamide groups were designed and synthesized. The target compounds were assayed for the effects on the insulin release of isolated rat pancreatic islets and the glucose transport in adipocytes of rats. Some of them exhibited high potency. Compound 10 also had potent antiplatelet activity and showed an excellent property to protect collagen-epinephrine-induced mice mortality as well as plasma glucose-lowering activity in vivo. The preliminary pharmacological profile of compound 10 showed that it might be useful in the treatment of diabetics with cardiovascular and nephropathy complications.