865811-65-0

Basic information

• Product Name: (S)-Modafinil Carboxylate Methyl Ester
• Synonyms: (S)-Modafinil Carboxylate Methyl Ester;2-[(S)-(DiphenylMethyl)sulfinyl]-acetic Acid Methyl Ester;Methyl (S)-(Benzhydrylsulfinyl)acetate
• CAS NO: 865811-65-0
• Molecular Formula: C₁₆H₁₆O₃S
• Molecular Weight: 290.37732
• Product Categories: Aromatics;Chiral Reagents;Drug Analogues;Intermediates & Fine Chemicals;Neurochemicals;Pharmaceuticals
• Mol File: 865811-65-0.mol
• Article Data: 4

Chemical Properties

• Melting Point: 101-104°C
• Boiling Point: 483.8±45.0 °C(Predicted)
• Appearance: /
• Density: 1.242±0.06 g/cm3(Predicted)
• Storage Temp.: Refrigerator
• CAS DataBase Reference: (S)-Modafinil Carboxylate Methyl Ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-Modafinil Carboxylate Methyl Ester(865811-65-0)
• EPA Substance Registry System: (S)-Modafinil Carboxylate Methyl Ester(865811-65-0)

Safety Data

• Hazardous Substances Data: 865811-65-0(Hazardous Substances Data)

Usage

Chemical Properties

Off-White Solid

Uses

Modafinil derivative.

Upstream product

• 74-88-4 methyl iodide 
• 112111-44-1 (S)-(+)-(diphenylmethanesulfinyl)acetic acid 
• 91-01-0 1,1-Diphenylmethanol 
• 63547-22-8 (benzhydrylthio)acetic acid 
• 63547-23-9 (diphenylmethyl)(ethyl acetate)sulfide 
• 63547-24-0 modafinil acid 
• 118286-24-1 methyl diphenylmethylmercaptoacetate 
• 776-74-9 Bromodiphenylmethane 

Downstream Products

• 118286-24-1 methyl diphenylmethylmercaptoacetate 

Relevant articles and documents

ION PAIR CATALYSIS OF TUNGSTATE AND MOLYBDATE

D The present invention relates to ion pair catalysts (I) comprising the cationic bisguanidinium ligand (A) and diperoxomolybdate anion (B). The present invention also relates to ion pair catalysts (III) comprising the cationic bisguanidinium ligand (C) and peroxotungstate anion (D). It further relates to the use of the said catalysts in the manufacture of enantiomerically enriched sulfoxides.

Asymmetric synthesis of modafinil and its derivatives by enantioselective oxidation of thioethers: comparison of various methods including synthesis in ionic liquids

The oxidation of 2-(benzhydrylthio)acetic acid and its derivatives was performed with various catalytic and stoichiometric enantioselective reagents, the best results being obtained with stoichiometric chiral oxaziridine 5. The use of [bmim][PF6] as a solvent with 5 gave slightly higher yields and, in the case of the model compound thioanisole, a reversal of the enantioselectivity.