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866102-73-0

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866102-73-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 866102-73-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,6,1,0 and 2 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 866102-73:
(8*8)+(7*6)+(6*6)+(5*1)+(4*0)+(3*2)+(2*7)+(1*3)=170
170 % 10 = 0
So 866102-73-0 is a valid CAS Registry Number.

866102-73-0Relevant articles and documents

Modifications to the tetracaine scaffold produce cyclic nucleotide-gated channel blockers with widely varying efficacies

Strassmaier, Timothy,Uma, Ramalinga,Ghatpande, Ambarish S.,Bandyopadhyay, Tapasree,Schaffer, Michelle,Witte, John,McDougal, Patrick G.,Brown, R. Lane,Karpen, Jeffrey W.

, p. 5805 - 5812 (2007/10/03)

Five new tetracaine analogues were synthesized and evaluated for potency of blockade of cyclic nucleotide-gated channels relative to a multiply charged tetracaine analogue described previously (4). Increased positive charge at the tertiary amine end of tetracaine results in higher potency and voltage dependence of block. Modifications that reduce the hydrophobic character at the butyl tail are deleterious to block. The tetracaine analogues described here have apparent affinities for CNGA1 channels that vary over nearly 8 orders of magnitude.

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