86611-53-2

Basic information

• Product Name: 9-(4-Methanesulfonylamino-2-methoxy-phenylamino)-6-methoxy-acridine-4-carboxylic acid methylamide; hydrochloride
• CAS NO: 86611-53-2
• Molecular Weight: 517.005
• Mol File: 86611-53-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 9-(4-Methanesulfonylamino-2-methoxy-phenylamino)-6-methoxy-acridine-4-carboxylic acid methylamide; hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 9-(4-Methanesulfonylamino-2-methoxy-phenylamino)-6-methoxy-acridine-4-carboxylic acid methylamide; hydrochloride(86611-53-2)
• EPA Substance Registry System: 9-(4-Methanesulfonylamino-2-methoxy-phenylamino)-6-methoxy-acridine-4-carboxylic acid methylamide; hydrochloride(86611-53-2)

Safety Data

• Hazardous Substances Data: 86611-53-2(Hazardous Substances Data)

Upstream product

• 84126-73-8 2-<(2-carboxyphenyl)amino>-4-methoxybenzoic acid 
• 118-92-3 anthranilic acid 
• 86611-40-7 3-methoxy-5-carboxy-9(10H)-acridanone 
• 21971-21-1 2-chloro-4-methoxybenzoic acid 
• 57165-06-7 N-(4-amino-3-methoxyphenyl)methanesulfonamide 

Relevant articles and documents

Potential antitumor agents. 38. 3-Substituted 5-carboxamido derivatives of amsacrine

The synthesis and biological evaluation of a series of 3-substituted 5-carboxamido derivatives of amsacrine (m-AMSA) are described. This series was developed as the result of previous quantitative structure-activity relationship (QSAR) studies of the antitumor activity of 9-anilinoacridine derivatives. In agreement with these studies, this class of compounds, possessing a variety of small nonpolar groups at the 3-position, together with very hydrophilic carboxamido groups at the 5-position, have high in vivo activity against animal leukemia models.