86618-06-6

Basic information

• Product Name: Benzeneacetic acid, 4-chloro-a-(1-Methylethyl)-, Methyl ester
• Synonyms: Benzeneacetic acid, 4-chloro-a-(1-Methylethyl)-, Methyl ester;2-(4-Chloro-phenyl)-3-methyl-butyric acid methyl ester
• CAS NO: 86618-06-6
• Molecular Formula: C₁₂H₁₅ClO₂
• Molecular Weight: 226.6993
• Mol File: 86618-06-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzeneacetic acid, 4-chloro-a-(1-Methylethyl)-, Methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetic acid, 4-chloro-a-(1-Methylethyl)-, Methyl ester(86618-06-6)
• EPA Substance Registry System: Benzeneacetic acid, 4-chloro-a-(1-Methylethyl)-, Methyl ester(86618-06-6)

Safety Data

• Hazardous Substances Data: 86618-06-6(Hazardous Substances Data)

Usage

Description

Benzeneacetic acid, 4-chloro-a-(1-Methylethyl)-, Methyl ester, also known as 4-chloro-alpha-isopropylbenzyl methyl ester, is a chemical compound that belongs to the class of aryl alkyl carboxylic acid derivatives. It is known for its potential anti-inflammatory and analgesic properties and is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals.

Uses

Used in Pharmaceutical Industry:
Benzeneacetic acid, 4-chloro-a-(1-Methylethyl)-, Methyl ester is used as an intermediate in the synthesis of various pharmaceuticals for its potential anti-inflammatory and analgesic properties.
Used in Agrochemical Industry:
Benzeneacetic acid, 4-chloro-a-(1-Methylethyl)-, Methyl ester is used as a precursor in the production of various agrochemicals.
It is important to handle this compound with care, as it can be toxic and harmful if not used or handled properly.

Upstream product

• 75-30-9 2-iodo-propane 
• 52449-43-1 (4-chloro-phenyl)-acetic acid methyl ester 
• 140-53-4 p-chlorobenzyl cyanide 
• 67-56-1 methanol 
• 2012-74-0 2-(4-chlorophenyl)-3-methylbutyric acid 
• 106-39-8 bromochlorobenzene 
• 924-50-5 Methyl 3,3-dimethylacrylate 

Downstream Products

• 55332-38-2 S-isopropyl-4-chlorophenylacetic acid 
• 63640-09-5 (R)-2-(4-chlorophenyl)-3-methylbutyric acid 
• 127641-48-9 (S)-2-(4-chlorophenyl)isovaleric acid methyl ester 
• 197018-23-8 (R)-2-(4-Chloro-phenyl)-3-methyl-butyric acid methyl ester 
• 88149-98-8 methyl-2-(4-hydroxyphenyl)-3-methylbutanoate 

Relevant articles and documents

Synthesis and Applications of Unquaternized C-Bound Boron Enolates

A general and facile method to prepare unquaternized C-bound boron enolates by a ligand-controlled O-to-C isomerization is reported. Using this protocol, C-bound pinacolboron enolates have been isolated in pure form for the first time, and have been fully characterized by NMR spectroscopy and X-ray crystallography. In contrast to the general perception, such C-boron enolates are stable without coordinative saturation at the boron. Moreover, C-boron enolates present reactivities that are distinct from the O-boron enolates, and their applications in C-O and C-C bond formations are demonstrated.

A Novel Electrogenerated Base. Alkylation of Methyl Arylacetates at the α-Methylene Group

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