86620-81-7

Basic information

• Product Name: 4-PIPERAZIN-1-YLMETHYL-BENZOIC ACID METHYL ESTER
• Synonyms: AKOS B022240;4-(1-PIPERAZINYL METHYL) BENZOIC ACID METHYL ESTER;4-(1-PIPERIYL METHYL) BENZOIC ACID METHYL ESTER;4-PIPERAZIN-1-YLMETHYL-BENZOIC ACID METHYL ESTER;ART-CHEM-BB B022240;METHYL 4-PIPERAZIN-1-YLMETHYLBENZOATE;METHYL 4-PIPERAZINE-1-YLMETHYLBENZOATE;4-(1-PIPERAZIYL METHYL) BENZOIC ACID METHYL ESTER
• CAS NO: 86620-81-7
• Molecular Formula: C₁₃H₁₈N₂O₂
• Molecular Weight: 234.29
• Product Categories: API intermediates
• Mol File: 86620-81-7.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 355.6 ºCat 760 mmHg
• Flash Point: 168.9 ºC
• Appearance: /
• Density: 1.117 g/cm³
• Vapor Pressure: 3.08E-05mmHg at 25°C
• Refractive Index: 1.544
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 4-PIPERAZIN-1-YLMETHYL-BENZOIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-PIPERAZIN-1-YLMETHYL-BENZOIC ACID METHYL ESTER(86620-81-7)
• EPA Substance Registry System: 4-PIPERAZIN-1-YLMETHYL-BENZOIC ACID METHYL ESTER(86620-81-7)

Safety Data

• Hazardous Substances Data: 86620-81-7(Hazardous Substances Data)

Usage

General Description

4-PIPERAZIN-1-YLMETHYL-BENZOIC ACID METHYL ESTER is a chemical compound that is derived from piperazine and benzoic acid. It is commonly used in the pharmaceutical industry as an intermediate in the synthesis of various drugs and pharmaceuticals. 4-PIPERAZIN-1-YLMETHYL-BENZOIC ACID METHYL ESTER exhibits a range of biological activities, including antipsychotic, antihistaminic, and anxiolytic effects. It is also used as a building block in the production of other organic compounds. Due to its versatile properties, 4-PIPERAZIN-1-YLMETHYL-BENZOIC ACID METHYL ESTER plays a crucial role in the development and production of numerous medications and pharmaceutical products.

InChI:InChI=1/C13H18N2O2/c1-17-13(16)12-4-2-11(3-5-12)10-15-8-6-14-7-9-15/h2-5,14H,6-10H2,1H3

Upstream product

• 110-85-0 piperazine 
• 2417-72-3 Methyl 4-(bromomethyl)benzoate 
• 142-64-3 piperazine dihydrochloride 
• 142-63-2 piperazine hexahydrate 
• 844891-11-8 tert-butyl 4-[(4-methoxycarbonylphenyl)methyl]piperazine-1-carboxylate 
• 619-66-9 4-Carboxybenzaldehyde 
• 34040-64-7 p-methyloxycarbonylbenzyl chloride 
• 1571-08-0 methyl 4-formylbenzoate 

Downstream Products

• 86620-80-6 Methyl 4-[1-(2-hydroxypropyl)-piperazin-4-ylmethyl]-benzoate 
• 895519-97-8 4-((4-ethylpiperazin-1-yl)methyl)benzoic acid 
• 208754-40-9 4-((4-propylpiperazin-1-yl)methyl)benzoic acid 
• 415951-48-3 C₁₅H₂₂N₂O₂ 

Relevant articles and documents

Synthesis, biological evaluation, and molecular docking of ((4-([1,2,4]triazolo[4,3-b][1,2,4,5]tetrazin-6-yl) piperazin-1-yl)methyl) benzohydrazide derivatives

A series of ((4-([1,2,4]triazolo[4,3-b][1,2,4,5] methyl) benzo-hydrazide derivatives was designed, synthesized, and evaluated for their inhibition activities against five tumor cells and c-Met kinase in vitro. These compounds were fully characterized by

ROR [gamma]t inhibitor, preparation method and application thereof

The invention relates to the technical field of medicines, in particular to an ROR [gamma]t inhibitor, a preparation method and application thereof. The invention also relates to a pharmaceutical composition containing the compound, a method for preparing the pharmaceutical composition, and application of the compound or the pharmaceutical composition in treatment or prevention of ROR [gamma]t-mediated cancers, inflammations or autoimmune diseases of mammals, especially human beings.

NEW FYN KINASE INHIBITORS

The invention relates to new selective FYN kinase inhibitors of Formula (I), pharmaceutical compositions containing them, and their use for the pharmacological treatment of pain and arthritis, including osteoarthritis and rheumatoid arthritis.