866216-24-2Relevant articles and documents
Pharmacophore-guided drug discovery investigations leading to bioactive 5-aminotetrahydropyrazolopyridines. Implications for the binding mode of heterocyclic dopamine D3 receptor agonists
Elsner, Jan,Boeckler, Frank,Heinemann, Frank W.,Hübner, Harald,Gmeiner, Peter
, p. 5771 - 5779 (2007/10/03)
Taking advantage of a 3D-QSAR based pharmacophore hypothesis, synthesis and biological evaluation of dopaminergic 5-aminotetrahydropyrazolo[1,5-a]pyridines are described. The data displayed substantial and selective D3 receptor affinity for the heterocycl