866216-63-9Relevant articles and documents
Synthesis of functionalized 2-alkylidene-tetrahydrofurans based on a [3+2] cyclization/bromination/palladium(0) cross-coupling strategy
Bellur, Esen,Langer, Peter
, p. 4815 - 4828 (2007/10/03)
The bromination of 2-alkylidene-tetrahydrofurans and 2-alkylidene- pyrrolidines - readily available through one-pot [3+2] cyclization reactions - afforded 2-alkylidene-1′-bromotetrahydrofurans, 2-alkylidene-3- bromotetrahydrofurans and 2-alkylidene-1′,3-dibromotetrahydrofurans and their pyrrolidine counterparts. 2-Alkylidene-1′-bromotetrahydrofurans were functionalized by performing Suzuki and Heck reactions. 2-Alkylidene-1′, 3-dibromotetrahydrofurans were successfully employed in novel double-Suzuki reactions. Wiley-VCH Verlag GmbH & Co. KGaA, 2005.