866235-10-1

Basic information

• Product Name: 2-benzyloxycarbonylamino-3-cyclohexyl-propionic acid 2,2,2-trifluoro-ethyl ester
• Synonyms: 2-benzyloxycarbonylamino-3-cyclohexyl-propionic acid 2,2,2-trifluoro-ethyl ester
• CAS NO: 866235-10-1
• Molecular Weight: 387.399
• Mol File: 866235-10-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-benzyloxycarbonylamino-3-cyclohexyl-propionic acid 2,2,2-trifluoro-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzyloxycarbonylamino-3-cyclohexyl-propionic acid 2,2,2-trifluoro-ethyl ester(866235-10-1)
• EPA Substance Registry System: 2-benzyloxycarbonylamino-3-cyclohexyl-propionic acid 2,2,2-trifluoro-ethyl ester(866235-10-1)

Safety Data

• Hazardous Substances Data: 866235-10-1(Hazardous Substances Data)

Upstream product

• 501-53-1 benzyl chloroformate 
• 4441-50-3 β-cyclohexylalanine 
• 75-89-8 2,2,2-trifluoroethanol 
• 119860-59-2 N-(Benzyloxycarbonyl)-2(S)-amino-3-cyclohexylpropionic acid 

Downstream Products

• 113828-93-6 (S)-2-Benzyloxycarbonylamino-3-cyclohexyl-propionic acid methyl ester 

Relevant articles and documents

Resolution of non-protein amino acids via Carica papaya lipase-catalyzed enantioselective transesterification

Carica papaya lipase-catalyzed transesterification of the 2,2,2-trifluoroethyl esters of N-benzyloxycarbonylated dl-amino acids carrying aliphatic side chains proceeded smoothly and, in almost all the cases, enantiospecifically (E = >200), affording the l-methyl esters and leaving the d-trifluoroethyl esters intact.