866327-65-3 Usage
Explanation
The molecular formula represents the number of atoms of each element present in a molecule of the compound.
Explanation
The chemical structure describes the arrangement of atoms and the type of chemical bonds between them.
3. Potential pharmacological properties
Explanation
The compound may have the ability to interact with biological targets and influence physiological processes, which could lead to potential applications in the field of medicine.
Explanation
The specific arrangement of atoms and functional groups in the compound may allow it to bind to and modulate the activity of specific biological targets, such as enzymes, receptors, or ion channels.
5. Influence on physiological processes
Explanation
The compound's interaction with biological targets may lead to changes in cellular or organismal function, which could have therapeutic or other pharmacological effects.
6. Further research needed
Explanation
More studies are required to fully understand the biological activity, potential applications, and safety profile of 1-[(5-HYDROXY-2-PYRIDINYL)CARBONYL]-PIPERIDINE.
Explanation
While the compound may have potential pharmacological properties, its specific applications and uses are not yet known and require further investigation.
Chemical structure
Piperidine derivative with a carbonyl group attached to a 5-hydroxy-2-pyridinyl moiety
Structural features
Interaction with biological targets
Potential applications
Unknown at this time
Check Digit Verification of cas no
The CAS Registry Mumber 866327-65-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,6,3,2 and 7 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 866327-65:
(8*8)+(7*6)+(6*6)+(5*3)+(4*2)+(3*7)+(2*6)+(1*5)=203
203 % 10 = 3
So 866327-65-3 is a valid CAS Registry Number.
866327-65-3Relevant articles and documents
Heterocyclic replacement of the central phenyl core of diamine-based histamine H3 receptor antagonists
Swanson, Devin M.,Shah, Chandra R.,Lord, Brian,Morton, Kirsten,Dvorak, Lisa K.,Mazur, Curt,Apodaca, Richard,Xiao, Wei,Boggs, Jamin D.,Feinstein, Mark,Wilson, Sandy J.,Barbier, Ann J.,Bonaventure, Pascal,Lovenberg, Timothy W.,Carruthers, Nicholas I.
experimental part, p. 4413 - 4425 (2009/12/24)
A series of small molecules consisting of a heterocyclic core flanked by two basic functionalities were synthesized and screened for in vitro affinity at the human histamine H3 receptor (hH3R). Nine of the twenty-eight compounds tested were found to possess a hH3R Ki of less than 5 nM and consisted of a diverse range of central hetero-aromatic linkers (pyridine, pyrazine, oxazole, isoxazole, thiazole, furan, thiophene, and pyrrole). One member of this series, (4-isopropyl-piperazin-1-yl)-(6-piperidin-1-ylmethyl-pyridin-3-yl)-methanone (37), was found to be a high affinity, selective antagonist that crosses the blood-brain barrier and occupies H3 receptors after oral administration in the rat.
