866474-71-7

Basic information

• Product Name: (E)-2,2-dimethyl-3-(3-methyl-6-m-tolylhex-3-enyl)oxirane
• Synonyms: (E)-2,2-dimethyl-3-(3-methyl-6-m-tolylhex-3-enyl)oxirane
• CAS NO: 866474-71-7
• Molecular Weight: 258.404
• Mol File: 866474-71-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (E)-2,2-dimethyl-3-(3-methyl-6-m-tolylhex-3-enyl)oxirane(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2,2-dimethyl-3-(3-methyl-6-m-tolylhex-3-enyl)oxirane(866474-71-7)
• EPA Substance Registry System: (E)-2,2-dimethyl-3-(3-methyl-6-m-tolylhex-3-enyl)oxirane(866474-71-7)

Safety Data

• Hazardous Substances Data: 866474-71-7(Hazardous Substances Data)

Upstream product

• 37715-31-4 (E)-5-(3,3-dimethyloxiran-2-yl)-3-methylpent-2-enyl acetate 
• 90531-94-5 (3-methylbenzyl)magnesium bromide 
• 29875-06-7 3-methylbenzylmagnesium chloride 

Relevant articles and documents

Transition-metal-catalyzed allylic substitution and titanocene-catalyzed epoxypolyene cyclization as a powerful tool for the preparation of terpenoids

Many biologically active substances are composed of sesquiterpene units linked to aromatic structures, especially substituted phenols. Here, we describe an efficient synthetic approach to this class of natural product from commercially available substances in a short sequence. The key transformations involve allylic substitution reactions using a palladium or copper catalyst and titanocene-catalyzed epoxypolyene cyclization reactions via radicals. The polycyclic core structures are accessed with high chemo- and stereocontrol. Wiley-VCH Verlag GmbH & Co. KGaA, 2006.

Efficient and stereoselective synthesis of precursors for epoxypolyene cyclizations via allylic substitutions

A catalytic and highly stereoselective approach to precursors for epoxypolyene cyclizations based on copper-catalyzed allylic substitutions is described. The method allows introduction of various aromatic, benzyl, and alkyl groups without affecting epoxides. The compounds obtained are valuable starting materials for the synthesis of natural products and biologically active substances. Georg Thieme Verlag Stuttgart.