866492-46-8

Basic information

• Product Name: (1S,2S,3R,4R)-3-[methyl(tosyl)amino]spiro[bicyclo[2.2.1]hept-5-ene-2,2'-oxirane]
• CAS NO: 866492-46-8
• Molecular Weight: 305.398
• Mol File: 866492-46-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1S,2S,3R,4R)-3-[methyl(tosyl)amino]spiro[bicyclo[2.2.1]hept-5-ene-2,2'-oxirane](CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2S,3R,4R)-3-[methyl(tosyl)amino]spiro[bicyclo[2.2.1]hept-5-ene-2,2'-oxirane](866492-46-8)
• EPA Substance Registry System: (1S,2S,3R,4R)-3-[methyl(tosyl)amino]spiro[bicyclo[2.2.1]hept-5-ene-2,2'-oxirane](866492-46-8)

Safety Data

• Hazardous Substances Data: 866492-46-8(Hazardous Substances Data)

Upstream product

• 136787-48-9 1-{2-{methyl[(4-methylphenyl)sulfonyl]amino}acetyl}pyrrolidine 
• 676-88-0 dimethyl(methylthio)sulfonium tetrafluoroborate 

Relevant articles and documents

First [4 + 2] cycloadditions involving the olefinic bond of an 'aldoketeniminium salt' (= N-alk-1-enylideneaminium salt)

Keteniminium triflates' (= N-alk-1-enylideneaminium trifluoromethanesulfonates; [MeN(Ts)CH=C= NR1(R2)] +TfO-) generated in situ from Nα- tosylsarcosinamides MeN(Ts)CH2CONR1(R2) unexpectedly react with cyclopenta-1,3-diene and cyclohexa-1,3-diene to give Diels-Alder reactions across the C=C bond of the cumulene. The use of N α-tosylsarcosinamides derived from chiral pyrrolidines allows the direct preparation of trinorbornenone derivative 6 in high enantiomer purity.